Deep brain stimulation electrode with photoacoustic and ultrasound imaging capabilities
US-12161295-B2 · Dec 10, 2024 · US
US9743840B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9743840-B2 |
| Application number | US-201514801533-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 16, 2015 |
| Priority date | Mar 25, 2013 |
| Publication date | Aug 29, 2017 |
| Grant date | Aug 29, 2017 |
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A flash lamp 32 excites a laser rod 31. A Q switch 35 which changes the loss of the optical resonator according to the voltage applied is inserted on the optical path of a pair of mirrors 33 and 34 forming the optical resonator. An optical path shutter 39 is provided on the optical path of laser emission light. In a first operation mode in which laser emission is performed, the optical path shutter 39 is opened and the voltage applied to the Q switch 35 is changed from a high voltage to, for example, 0 V to emit pulsed laser light after the flash lamp 32 excites the laser rod 31. In a second operation mode in which the laser emission is interrupted and waited for, the optical path shutter 39 is closed and the voltage applied to the Q switch 35 is, for example, 0 V.
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What is claimed is: 1. A photoacoustic measurement device comprising: a laser medium; an excitation unit that excites the laser medium; an optical resonator including a pair of mirrors that face each other with the laser medium interposed therebetween; a Q switch that is provided on an optical path of the optical resonator and changes optical loss of the optical resonator, according to a voltage applied, such that the optical loss of the optical resonator when a first voltage is applied to the Q switch is more than the optical loss of the optical resonator when a second voltage lower than the first voltage is applied to the Q switch; a laser light source that is provided on an optical path of laser emission light and has an optical path shutter which switches the transmission and blocking of the laser emission light; an acoustic wave detection unit that, after light is emitted from the laser light source to a subject, detects a photoacoustic wave generated by the emission of the light; a photoacoustic signal processing unit that performs signal processing for the photoacoustic wave; and a control unit that performs control such that, in a first operation mode in which laser emission is performed, the optical path shutter transmits the light from the laser light source and the voltage applied to the Q switch is changed from the first voltage to the second voltage to emit pulsed laser light after the excitation unit excites the laser medium; and such that, in a second operation mode in which the laser emission is interrupted and waited for, the optical path shutter blocks the light from the laser light source and the second voltage is applied to the Q switch, wherein the laser light source has an interrupter closing detector that detects the closing of the optical path shutter, and when the interrupter closing detector detects that the optical path shutter is closed, the control unit controls the voltage applied to the Q switch to be the second voltage. 2. The photoacoustic measurement device according to claim 1 , wherein, in the second operation mode, the excitation unit periodically excites the laser medium. 3. The photoacoustic measurement device according to claim 2 , wherein the second voltage is 0 V. 4. The photoacoustic measurement device according to claim 3 , wherein the Q switch gives a predetermined phase difference between a polarized component which is parallel to an optical axis of transmitted light and a polarized component which is perpendicular to the optical axis when the first voltage is applied and does not give a phase difference between the polarized component which is parallel to the optical axis of the transmitted light and the polarized component which is perpendicular to the optical axis when the second voltage is applied. 5. The photoacoustic measurement device according to claim 3 , wherein the Q switch functions as a quarter-wave plate for light with a wavelength of laser light when the first voltage is applied. 6. The photoacoustic measurement device according to claim 4 , wherein the Q switch functions as a quarter-wave plate for light with a wavelength of laser light when the first voltage is applied. 7. The photoacoustic measurement device according to claim 2 , wherein the Q switch gives a predetermined phase difference between a polarized component which is parallel to an optical axis of transmitted light and a polarized component which is perpendicular to the optical axis when the first voltage is applied and does not give a phase difference between the polarized component which is parallel to the optical axis of the transmitted light and the polarized component which is perpendicular to the optical axis when the second voltage is applied. 8. The photoacoustic measurement device according to claim 7 , wherein the Q switch functions as a quarter-wave plate for light with a wavelength of laser light when the first voltage is applied. 9. The photoacoustic measurement device according to claim 2 , wherein the Q switch functions as a quarter-wave plate for light with a wavelength of laser light when the first voltage is applied. 10. The photoacoustic measurement device according to claim 1 , wherein the second voltage is 0 V. 11. The photoacoustic measurement device according to claim 10 , wherein the Q switch gives a predetermined phase difference between a polarized component which is parallel to an optical axis of transmitted light and a polarized component which is perpendicular to the optical axis when the first voltage is applied and does not give a phase difference between the polarized component which is parallel to the optical axis of the transmitted light and the polarized component which is perpendicular to the optical axis when the second voltage is applied. 12. The photoacoustic measurement device according to claim 11 , wherein the Q switch functions as a quarter-wave plate for light with a wavelength of laser light when the first voltage is applied. 13. The photoacoustic measurement device according to claim 10 , wherein the Q switch functions as a quarter-wave plate for light with a wavelength of laser light when the first voltage is applied. 14. The photoacoustic measurement device according to claim 1 , wherein the Q switch gives a predetermined phase difference between a polarized component which is parallel to an optical axis of transmitted light and a polarized component which is perpendicular to the optical axis when the first voltage is applied and does not give a phase difference between the polarized component which is parallel to the optical axis of the transmitted light and the polarized component which is perpendicular to the optical axis when the second voltage is applied. 15. The photoacoustic measurement device according to claim 14 , wherein the Q switch functions as a quarter-wave plate for light with a wavelength of laser light when the first voltage is applied. 16. The photoacoustic measurement device according to claim 1 , wherein the Q switch functions as a quarter-wave plate for light with a wavelength of laser light when the first voltage is applied. 17. The photoacoustic measurement device according to claim 1 , wherein the photoacoustic signal processing unit generates a photoacoustic image on the basis of the photoacoustic signal. 18. The photoacoustic measurement device according to claim 1 , wherein the photoacoustic measurement device operates in the first operation mode when an instruction to measure the photoacoustic signal is input and operates in the second operation mode when an instruction to stop the measurement of the photoacoustic signal is input. 19. The photoacoustic measurement device according to claim 1 , wherein, in the first operation mode, after changing the voltage applied to the Q switch from the first voltage to the second voltage, the control unit performs control such that the first voltage is applied to the Q switch. 20. A laser light source used in the photoacoustic measurement device according to claim 1 , comprising: a laser medium; an excitation unit that excites the laser medium; an optical resonator including a pair of mirrors that face each other with the laser medium interposed therebetween; a Q switch that is provided on an optical path of the optical resonator and changes optical loss of the optical resonator, according to a voltage applied, such that the optical loss of the optical resonator when a first voltage is applied to the Q switch is more than the
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