Multi-Modal Fluorescence Imaging Flow Cytometry System
US-2024353309-A1 · Oct 24, 2024 · US
US9739992B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9739992-B2 |
| Application number | US-201314441981-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 25, 2013 |
| Priority date | Nov 12, 2012 |
| Publication date | Aug 22, 2017 |
| Grant date | Aug 22, 2017 |
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A light irradiation device is an apparatus for irradiating an irradiation object, and includes a light source outputting readout light L 1 , a spatial light modulator modulating the readout light L 1 in phase to output modulated light L 2 , and a both-sided telecentric optical system including a first lens optically coupled to a phase modulation plane of the spatial light modulator and a second lens optically coupled between the first lens and the irradiation object, and optically coupling the phase modulation plane and the irradiation object. An optical distance between the phase modulation plane and the first lens is substantially equal to a focal length of the first lens. The spatial light modulator displays a Fresnel type kinoform on the phase modulation plane.
Opening claim text (preview).
The invention claimed is: 1. A light irradiation apparatus for irradiating an irradiation object with light, comprising: a light source configured to output light; a spatial light modulator comprising a phase modulation plane including a plurality of two-dimensionally arrayed regions, and configured to display a Fresnel type kinoform on the phase modulation plane and modulate the light in phase in each of the plurality of regions to output modulated light; and a both-sided telecentric optical system comprising a first lens and a second lens, and optically coupling the phase modulation plane and an irradiation object, the first lens being optically coupled between the phase modulation plane of the spatial light modulator and the second lens, and the second lens being optically coupled between the first lens and the irradiation object, and a distance between the second lens and the irradiation object is configured to remain constant, wherein an optical distance between the phase modulation plane and the first lens is substantially equal to a focal length of the first lens, and a light condensing position of the modulated light in an optical axis direction is adjusted by changing a focal length of the Fresnel type kinoform. 2. The light irradiation apparatus according to claim 1 , wherein the Fresnel type kinoform comprises a kinoform reducing the modulated light in diameter toward the first lens. 3. The light irradiation apparatus according to claim 1 , wherein the Fresnel type kinoform comprises a kinoform expanding the modulated light in diameter toward the first lens. 4. The light irradiation apparatus according to claim 1 , wherein the Fresnel type kinoform comprises a kinoform making a shape of the modulated light on the irradiation object a circular shape, a rectangular shape, or a linear shape.
Phase-only modulation · CPC title
Semiconductor devices · CPC title
affording illumination for phase-contrast observation · CPC title
Dividing the beam into multiple beams, e.g. multi-focusing · CPC title
adaptive optics, e.g. wavefront correction · CPC title
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