Use of tetrahydroindazolylbenzamide and tetrahydroindolylbenzamide derivatives for the treatment of human immunodeficiency virus (hiv) and acquired immune deficiency syndrome (aids)
US-2016143884-A1 · May 26, 2016 · US
Antimicrobial compositions, methods of use, and methods of treatment of infections
US9737509B1 · US · B1
| Field | Value |
|---|---|
| Publication number | US-9737509-B1 |
| Application number | US-201615162698-A |
| Country | US |
| Kind code | B1 |
| Filing date | May 24, 2016 |
| Priority date | May 26, 2015 |
| Publication date | Aug 22, 2017 |
| Grant date | Aug 22, 2017 |
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- Title
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Abstract
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The present disclosure provides compositions including a compound (e.g., compounds A-D), pharmaceutical compositions including the compound, methods of treatment of a condition (e.g., an infection) or disease, methods of treatment using compositions or pharmaceutical compositions, and the like.
First claim
Opening claim text (preview).
We claim: 1. A pharmaceutical composition comprising a therapeutically effective amount of a compound, or a pharmaceutically acceptable salt of the compound, and a pharmaceutically acceptable carrier, to treat a bacterial or protozoan infection, wherein the compound has the following structure: wherein R is NH 2 , Me, Et, iPr, CH 2 OMe, cyclopentyl, or p-tolyl. 2. The composition of claim 1 , wherein the infection is at least one of: Leishmania, Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa , or Enterobacter cloacae. 3. A composition comprising a compound, wherein the compound has the following structure: wherein R is NH 2 , Me, Et, iPr, CH 2 OMe, cyclopentyl, or p-tolyl. 4. A method of treating an infection comprising: delivering to a subject in need thereof, a pharmaceutical composition, wherein the pharmaceutical composition includes a therapeutically effective amount of a compound, or a pharmaceutically acceptable salt of the compound, and a pharmaceutically acceptable carrier, to treat the bacterial or protozoan, wherein the compound has the following structure: wherein R is NH 2 , Me, Et, iPr, CH 2 OMe, cyclopentyl, or p-tolyl. 5. The method of claim 4 , wherein the infection is at least one of: Leishmania, Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa , or Enterobacter cloacae.
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Classifications
8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine · CPC title
ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine · CPC title
Quinolines; Isoquinolines · CPC title
containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine · CPC title
the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline · CPC title
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- What does patent US9737509B1 cover?
- The present disclosure provides compositions including a compound (e.g., compounds A-D), pharmaceutical compositions including the compound, methods of treatment of a condition (e.g., an infection) or disease, methods of treatment using compositions or pharmaceutical compositions, and the like.
- Who is the assignee on this patent?
- Leahy James William, Kyle Dennis Edward, Vesely Brian Andrew, and 4 more
- What technology area does this patent fall under?
- Primary CPC classification A61K31/416. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Aug 22 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B1). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 2 related publications on this page (citations in our corpus or others sharing the same primary CPC).