Calebin A for hepatic steatosis

US9737502B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9737502-B2
Application numberUS-201514690438-A
CountryUS
Kind codeB2
Filing dateApr 19, 2015
Priority dateJan 10, 2011
Publication dateAug 22, 2017
Grant dateAug 22, 2017

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

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The present invention discloses the potential of Calebin A in attenuating high fat diet (HFD) induced hepatic steatosis in mammals.

First claim

Opening claim text (preview).

We claim: 1. A method of restoring adipocyte size in the fat tissue of obese mammals, said method comprising step of bringing into contact (a) enlarged mammalian adipocytes wherein enlargement resulting from a high fat diet regime, and (b) Calebin-A by orally administering effective concentrations of Calebin-A to said mammals, to achieve the effect of restoration of normal adipocyte size in fat tissue. 2. A method of treating high fat diet (HFD) induced hepatic steatosis in mammals, said method comprising step of bringing into contact HFD affected hepatic cells marked by inflammatory infiltration, hepatocellular ballooning degeneration and high triglyceride levels with Calebin-A by orally administering to said mammals effective concentrations of Calebin-A to bring about the effect of attenuation of hepatic steatosis in a dose dependant manner.

Assignees

Inventors

Classifications

  • from plants · CPC title

  • A61K31/235Primary

    having an aromatic ring attached to a carboxyl group · CPC title

  • Adipocytes; Adipose tissue · CPC title

  • of acids having aromatic rings, e.g. benactizyne, clofibrate · CPC title

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Frequently asked questions

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What does patent US9737502B2 cover?
The present invention discloses the potential of Calebin A in attenuating high fat diet (HFD) induced hepatic steatosis in mammals.
Who is the assignee on this patent?
Nagabhushanam Kalyanam, Majeed Anju, Majeed Muhammed, and 1 more
What technology area does this patent fall under?
Primary CPC classification A61K31/235. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Aug 22 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).