Methods and compositions for the treatment of proliferative disorders
US-2015044278-A1 · Feb 12, 2015 · US
US9730941B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9730941-B2 |
| Application number | US-201314406401-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 7, 2013 |
| Priority date | Jun 7, 2012 |
| Publication date | Aug 15, 2017 |
| Grant date | Aug 15, 2017 |
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The invention features compositions and methods for inhibiting the Pin1 protein, and the treatment of disorders characterized by elevated Pin1 levels.
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What is claimed is: 1. A method of inhibiting Pin1 by contacting Pin1 with a compound having the structure selected from Compound 48 and Compound 49: wherein said compound is a Pin1 inhibitor. 2. The method of claim 1 , wherein said Pin1 is in a cell. 3. The method of claim 2 , wherein said cell is a human cell.
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