Method and apparatus for penetrating tissue

Patent metadata

Field	Value
Publication number	US-9724021-B2
Application number	US-201414563833-A
Country	US
Kind code	B2
Filing date	Dec 8, 2014
Priority date	Apr 19, 2002
Publication date	Aug 8, 2017
Grant date	Aug 8, 2017

Abstract

A body fluid sampling system for use on a tissue site includes a single drive force generator. A plurality of penetrating members are operatively coupled to the force generator. The force generator moves each of the members along a path out of a housing with a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. A flexible support member couples the penetrating members to define a linear array. The support member is movable and configured to move each of the penetrating members to a launch position associated with the force generator.

First claim

What is claimed is:

1. A body fluid sampling system for use on a target tissue site, the system comprising:
a controllable drive force generator;
a plurality of penetrating members operatively coupled to said controllable drive force generator, each of a penetrating member of the plurality of penetrating members at least partially positioned adjacent to an analyte detecting member in a sample chamber, the sample chamber configured to receive body fluid from a wound in tissue created by each of a penetrating member of the plurality of penetrating member, and the analyte detecting member being configured to determine at least one analyte level using a body fluid sample of less than about 1 microliter;
a feedback loop coupled to a processor, the processor storing controllable drive force generator profiles in a memory, the processor configured to select a controllable drive force generator profile from a set of alternative controllable drive force generator profiles based on a controllable drive force generator performance, the processor configured to modify a selected controllable drive force generator profile and in response modulate a power from a power supply to the controllable drive force generator to provide a controllable velocity trajectory for each of a penetrating member of the plurality of penetrating members into the tissue site and out of the tissue site, the processor configured to monitor position and speed of each of a penetrating member of the plurality of penetrating members as it moves in a first direction to and through the target tissue site;
a support member with a surface that carries the plurality of penetrating members, said support member being movable to move each of a penetrating member of the plurality of penetrating members to a launch position associated with said controllable drive force generator.

2. The system of claim 1 , further comprising a plurality of analyte detecting members positioned to receive body fluid.

3. The system of claim 1 , wherein:
the sample chamber has an opening for transport of a body fluid into the sample chamber, the sample chamber being sized to receive no more than 0.75 microliter of the body fluid.

4. The system of claim 1 , wherein:
the sample chamber has an opening for transport of a body fluid into the sample chamber, the sample chamber being sized to receive no more than 0.5 microliter of the body fluid.

5. The system of claim 1 , wherein:
the sample chamber has an opening for transport of a body fluid into the sample chamber, the sample chamber being sized to receive no more than 0.25 microliter of the body fluid.

6. The system of claim 1 , wherein:
the sample chamber has an opening for transport of a body fluid into the sample chamber, the sample chamber being sized to receive no more than 0.1 microliter of the body fluid.

7. The system of claim 1 , wherein:
the analyte detecting member being configured to determine a concentration of an analyte in a body fluid using a sample that does not exceed a volume of 1 microliter of a body fluid disposed in the sample chamber.

8. The system of claim 1 , wherein the analyte detecting member being configured to determine a concentration of an analyte in a body fluid using a sample that does not exceed a volume of 0.75 microliter of a body fluid disposed in the sample chamber.

9. The system of claim 1 , wherein the analyte detecting member being configured to determine a concentration of an analyte in a body fluid using a sample that does not exceed a volume of 0.5 microliter of a body fluid disposed in the sample chamber.

10. The system of claim 1 , wherein the analyte detecting member being configured to determine a concentration of an analyte in a body fluid using a sample that does not exceed a volume of 0.25 microliter of a body fluid disposed in the sample chamber.

11. The system of claim 1 , wherein the analyte detecting member being configured to determine a concentration of an analyte in a body fluid using a sample that does not exceed a volume of 0.1 microliter of a body fluid disposed in the sample chamber.

12. The system of claim 1 , wherein each of a penetrating member of the plurality of penetrating members is an elongate member without molded attachments.

13. The system of claim 1 ,
wherein a penetrating member exit is configured to be positioned against the tissue site when each of a penetrating member of the plurality of penetrating members contacts the tissue site.

Assignees

• Sanofi Aventis Deutschland

Inventors

• Freeman Dominique M
• Boecker Dirk
• Alden Don

Classifications

• A61B5/15178

  Stocking means comprising separate compartments or units for new and for used piercing elements (separate compartments for used piercing elements in piercing devices A61B5/15184) · CPC title

• A61B5/1455

  using optical sensors, e.g. spectral photometrical oximeters · CPC title

• A61B5/15163

  Characterized by propelling the piercing element in an axial direction relative to the disc · CPC title

• A61B5/15123

  comprising magnets or solenoids · CPC title

• A61B5/15186

  Devices loaded with a single lancet, i.e. a single lancet with or without a casing is loaded into a reusable drive device and then discarded after use; drive devices reloadable for multiple use · CPC title