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PSMA-targeting imaging agents
US9713649B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9713649-B2 |
| Application number | US-201514605124-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 26, 2015 |
| Priority date | Jan 24, 2014 |
| Publication date | Jul 25, 2017 |
| Grant date | Jul 25, 2017 |
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- Title
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- Abstract
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Abstract
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A PSMA-specific imaging agent comprising a compound according to formula I: are described, wherein S 1 is an organic spacer group having from 5 to 30 carbons, A is an amino acid forming a portion of a negatively charged peptide oligomer, n is from 3 to 6, S 2 is an organic spacer group having from 5 to 15 carbons, and I is an imaging group, and pharmaceutically acceptable salts thereof. The PSMA-specific imaging agents can be used to image PSMA within a tissue region to guide the treatment of diseases such as prostate cancer.
First claim
Opening claim text (preview).
What is claimed is: 1. A PSMA-specific imaging agent comprising a compound having the structure of formula: and pharmaceutically acceptable salts thereof.
Assignees
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Classifications
- A61K49/0032Primary
Methine dyes, e.g. cyanine dyes · CPC title
Amines, polyamines, e.g. spermine, spermidine, amino acids, (bis)guanidines · CPC title
Small organic molecules (oligomers, polymers, dendrimers A61K49/0054) · CPC title
conjugates with a carrier being an organic compounds · CPC title
carboxylic acid carriers, fatty acids (amino acids A61K51/0406) · CPC title
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- What does patent US9713649B2 cover?
- A PSMA-specific imaging agent comprising a compound according to formula I: are described, wherein S 1 is an organic spacer group having from 5 to 30 carbons, A is an amino acid forming a portion of a negatively charged peptide oligomer, n is from 3 to 6, S 2 is an organic spacer group having from 5 to 15 carbons, and I is an imaging group, and pharmaceutically acce…
- Who is the assignee on this patent?
- Cleveland Clinic Found
- What technology area does this patent fall under?
- Primary CPC classification A61K49/0032. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Jul 25 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).