Wide QRS detector

Patent metadata

Field	Value
Publication number	US-9713432-B2
Application number	US-201213472563-A
Country	US
Kind code	B2
Filing date	May 16, 2012
Priority date	May 31, 2011
Publication date	Jul 25, 2017
Grant date	Jul 25, 2017

Abstract

A system comprises a cardiac signal sensing circuit and a processor circuit. To detect a QRS duration, the processor circuit determines an isoelectric amplitude value of the cardiac signal segment, identifies a time where the cardiac signal segment amplitude deviates from the first isoelectric amplitude value by a specified threshold deviation value as a Q time, determines an isoelectric value time after the determined maxima and minima times that the cardiac signal segment returns to the same or a different isoelectric amplitude value, identifies a time that follows both the determined maxima and minima times and precedes the isoelectric value time as an S time, wherein the cardiac signal segment amplitude at the identified S time satisfies a specified amplitude change criterion from an isoelectric amplitude value, and determines a time duration of the QRS complex in the cardiac signal segment using the identified Q and S times.

First claim

What is claimed is:

1. A system comprising:
a cardiac signal sensing circuit configured to sense a cardiac signal segment when operatively coupled to electrodes that contact a patient, wherein the cardiac signal segment includes a QRS complex;
a processor circuit communicatively coupled to the cardiac signal sensing circuit, wherein the processor circuit includes:
a peak detector circuit configured to determine a time of a maxima and a time of a minima in the sensed cardiac signal segment; and
a QRS complex time duration circuit configured to:
determine an isoelectric amplitude value of the cardiac signal segment;
identify, as a Q time in the QRS complex, a time where the amplitude of the sensed cardiac signal segment deviates from the first isoelectric amplitude value by a specified amplitude threshold value;
determine an isoelectric value time after the determined maxima and minima times that the cardiac signal segment returns to the same or a different isoelectric amplitude value;
identify, as an S time in the QRS complex, a time that follows both the determined maxima and minima times and precedes the isoelectric value time, wherein the amplitude of the sensed cardiac signal segment at the identified S time satisfies a specified amplitude change criterion from the isoelectric amplitude value, and wherein the amplitude change criterion is chosen according to a determined relation of the maxima time to the minima time; and
generate a value of a time duration of the QRS complex in the cardiac signal segment using the identified Q time and S time.

2. The system of claim 1 , wherein the QRS complex time duration circuit is configured to:
calculate a derivative of the portion of the cardiac signal segment that follows both the determined maxima and minima times and precedes the isoelectric value time;
identify as the S time, when the minima time occurs after the maxima time, a time of a maximum of the derivative of the cardiac signal segment portion; and
identify as the S time, when the maxima time occurs after the minima time, a time of a minimum of the derivative of the cardiac signal segment portion.

3. The system of claim 1 , wherein the QRS complex time duration circuit is configured to:
identify as the S time, when the minima time occurs after the maxima time, a time that the amplitude of the cardiac signal is a specified fraction of the difference between the minima and the isoelectric amplitude value at the isoelectric value time; and
identify as the S time, when the maxima time occurs after the minima time, a time where the amplitude of the cardiac signal is a specified fraction of the difference between the maxima and the isoelectric amplitude value.

4. The system of claim 1 , vherein the QRS complex time duration circuit is configured to:
identify as the S time, when the minima time occurs after the maxima time, a specified fraction of the time duration from the time of the minima to the isoelectric value time; and
identify as the S time, when the maxima time occurs after the minima time, a specified fraction of the time duration from the time of the maxima to the isoelectric value time.

5. The system of claim 1 , wherein the cardiac signal sensing circuit is implantable and includes a unipolar sensing channel.

6. The system of claim 5 , wherein the cardiac signal sensing circuit is within an implantable housing, and wherein the unipolar sensing channel includes a first electrode configured to provide at least one of cardioversion or defibrillation shock therapy and a second electrode formed using the implantable housing.

7. The system of claim 5 , wherein the cardiac signal sensing circuit is within an implantable housing, and wherein the unipolar sensing channel includes a first electrode configured to sense a cardiac signal in a right ventricle and a second electrode formed using the implantable housing.

8. The system of claim 1 , wherein the processor circuit includes a bundle branch block (BBB) detection circuit configured to:
generate an indication of left bundle branch block (LBBB) when the minima time occurs after the maxima time and the time duration of the QRS complex exceeds a specified threshold time duration value; and
provide the indication of LBBB to at least one of a user or process.

9. The system of claim 1 , wherein the processor circuit includes a BBB detection circuit configured to:
generate an indication of possible right bundle branch block (RBBB) when the maxima time occurs after the minima time; and
provide the indication to at least one of a user or process.

10. The system of claim 1 , wherein the QRS complex time duration circuit is configured to:
calculate a confidence interval for the QRS complex time duration value using QRS complex time durations calculated for N heart beats, wherein N is a positive integer; and
provide the determined QRS complex time duration value and confidence interval value to at least one of a user or process.

11. The system of claim 10 , wherein the processor circuit includes a BBB detection circuit configured to generate an indication of at least one of RBBB or LBBB according to the time relationship of the determined maxima and minima times, the determined QRS complex time duration, and the calculated confidence interval for the QRS complex time duration.

12. The system of claim 1 , including:
a trend buffer circuit integral to or communicatively coupled to the processor circuit and configured to store determined time durations for QRS complexes; and
wherein the processor circuit is configured to trend the time duration using stored time duration values and to change an amount of storage in the trend buffer circuit in response to detecting at least one of:
an expected value of the width of the QRS complex determined from the trending; and

a deviation of the width e QRS complex from an expected trend value of the width.

13. The system of claim 1 , wherein the implantable cardiac signal sensing circuit and the processor circuit are included in an implantable medical device.

14. The system of claim 1 , wherein the implantable cardiac signal sensing circuit is included in an implantable medical device and the processor circuit is included in a second device.

15. An ambulatory medical device comprising:
a cardiac signal sensing circuit configured to sense a cardiac signal segment when operatively coupled to electrodes that contact a patient, wherein the cardiac signal segment includes a QRS complex;
a peak detector circuit configured to determine a time of a maxima and a time of a minima in the cardiac signal segment; and
a QRS complex time duration circuit is configured to:
determine a time of return to an isoelectric amplitude value after the determined maxima and minima times of the cardiac signal segment;
generate a value of an S time of the QRS complex as a time, following the determined maxima and minima times and preceding the time of return to the isoelectric amplitude value, at which the amplitude of the sensed cardiac signal segment satisfies a specified amplitude change criterion from the isoelectric amplitude value, and wherein the amplitude change criterion is chosen according to a determined relation of the maxima time to the minima time; and
calculate and store a value of time duration of the QRS complex using the generated value of the S time.

16. The ambulatory medical device of claim 15 , wherein the QRS complex time duration circuit is configured to generate an indication of a type of bundle breach block (BBB) using the calculated time duration of the QRS complex and the dete

Assignees

• Patangay Abhilash
• Shome Shibaji
• Thakur Pramodsingh Hirasingh
• Li Dan
• Martin Stevens L
• Cardiac Pacemakers Inc

Inventors

• Patangay Abhilash
• Shome Shibaji
• Thakur Pramodsingh Hirasingh
• Li Dan
• Martin Stevens L

Classifications

• A61N1/36507

  controlled by gradient or slope of the heart potential · CPC title

• A61N1/3627

  for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy · CPC title

• A61B5/7239

  using differentiation including higher order derivatives · CPC title

• A61B5/0452

  Human Necessities · mapped topic

• A61N1/37

  Monitoring; Protecting · CPC title