Black blood MRI using a stimulated echo pulse sequence with flow sensitization gradients

Patent metadata

Field	Value
Publication number	US-9709644-B2
Application number	US-201214112183-A
Country	US
Kind code	B2
Filing date	Apr 12, 2012
Priority date	Apr 21, 2011
Publication date	Jul 18, 2017
Grant date	Jul 18, 2017

Abstract

A black blood magnetic resonance imaging sequence is performed using a magnetic resonance scanner. The sequence includes: applying a first flow sensitization gradient; applying a spoiler gradient after applying the first flow sensitization gradient; applying a second flow sensitization gradient after applying the spoiler gradient wherein the second flow sensitization gradient has area equal to the first flow sensitization gradient but of opposite polarity; applying a slice-selective radio frequency excitation pulse after applying the spoiler gradient; and performing a magnetic resonance readout after applying the second flow sensitization gradient and after applying the slice selective radio frequency excitation. The readout acquires magnetic resonance imaging data having blood signal suppression in the region excited by the slice-selective radio frequency excitation pulse. The magnetic resonance imaging data is suitably reconstructed to generate a black blood image that may be displayed.

First claim

Having described the preferred embodiments, the invention is now claimed to be:

1. A method comprising:
performing a local excitation black blood imaging (LOBBI) sequence using a magnetic resonance (MR) scanner ( 10 ), the performing of the LOBBI sequence including:
applying a first flow sensitization gradient for in-plane flow sensitization with a 90° radio frequency pulse preceding the first flow sensitization gradient and a −90° tip-up radio frequency pulse following the first flow sensitization gradient,
applying a spoiler gradient after applying the first flow sensitization gradient,
applying a second flow sensitization gradient for in-plane flow sensitization after applying the spoiler gradient wherein the second flow sensitization gradient has area equal to the first flow sensitization gradient but of opposite polarity, and
performing an acquisition module including:
applying a slice-selective radio frequency excitation pulse after applying the spoiler gradient, and
performing a magnetic resonance readout acquisition after applying the slice-selective radio frequency excitation pulse,
wherein at least a portion of the second flow sensitization gradient is applied after applying the slice-selective radio frequency excitation pulse.

2. The method of claim 1 , wherein the LOBBI sequence includes performing n repetitions of the acquisition module where n>1.

3. The method of claim 1 , wherein the performing comprises:
performing the LOBBI sequence using the MR scanner and a local excitation coil having a coverage area of less than 20 centimeters.

4. The method of claim 1 , wherein the performing comprises:
performing the LOBBI sequence using the MR scanner and a local excitation coil having a coverage area of less than 10 centimeters.

5. The method of claim 1 , wherein the performing of the LOBBI sequence acquires magnetic resonance imaging data and the method further comprises:
reconstructing the magnetic resonance imaging data to generate an image having black blood contrast.

6. The method of claim 5 , further comprising:
displaying the image having black blood contrast.

7. The method of claim 1 wherein the applying a second flow sensitization gradient after applying the spoiler gradient comprises:
applying the entire second flow sensitization gradient after applying the slice-selective radio frequency excitation pulse.

8. The method of claim 1 wherein the applying a second flow sensitization gradient after applying the spoiler gradient comprises:
applying a first portion of the second flow sensitization gradient before applying the slice-selective radio frequency excitation pulse, and
applying a second portion of the second flow sensitization gradient after applying the slice-selective radio frequency excitation pulse;
wherein the first and second portions of the second flow sensitization gradient have a combined area equal to the area of the first flow sensitization gradient.

9. The method of claim 1 wherein the black blood magnetic resonance imaging sequence is a spin echo sequence.

10. The method of claim 1 wherein a time interval between applying the slice-selective radio frequency excitation pulse and performing the magnetic resonance readout is less than or about 10 ms.

11. A non-transitory storage medium storing instructions executable by an electronic data processing device operating in conjunction with a magnetic resonance scanner controlled by the electronic data processing device to perform a method as set forth in claim 1 .

12. An apparatus comprising:
a magnetic resonance scanner; and
an electronic data processing device programmed to perform a method as set forth in claim 1 .

Assignees

• Wang Jinnan
• Börnert Peter
• Yuan Chun
• Univ Washington
• Koninklijke Philips Nv

Inventors

• Wang Jinnan
• Börnert Peter
• Yuan Chun

Classifications

• G01R33/30 Primary

  Sample handling arrangements, e.g. sample cells, spinning mechanisms · CPC title

• G01R33/56316 Primary

  involving phase contrast techniques · CPC title

• G01R33/5635

  Angiography, e.g. contrast-enhanced angiography [CE-MRA] or time-of-flight angiography [TOF-MRA] · CPC title