Drug delivery device and method for a drug delivery device

Patent metadata

Field	Value
Publication number	US-9707352-B2
Application number	US-201214346507-A
Country	US
Kind code	B2
Filing date	Sep 27, 2012
Priority date	Sep 29, 2011
Publication date	Jul 18, 2017
Grant date	Jul 18, 2017

Abstract

A drug delivery device is provided comprising a housing comprising a distal end and a proximal end and a cartridge adapted and arranged to contain at least one dose of a drug, a bung being movably arranged within the cartridge. In an initial state of the device, the bung is arranged in a proximal end position with respect to the cartridge. The device further comprises a piston rod adapted and arranged to move the bung in the distal direction with respect to the cartridge for delivering a dose of the drug. The device further comprises a mechanism operable such that, after a dose delivery operation was completed, the piston rod is moved into the proximal direction with respect to the bung by a back off distance (D), wherein in the initial state, a distance between a distal end of the piston rod and a proximal end of the bung is greater than zero, with the distance between the piston rod and the bung in the initial state being defined by the back off distance (D). Furthermore, a method for assembling a drug delivery device is provided.

First claim

The invention claimed is:

1. A drug delivery device comprising:
a housing comprising a distal end and a proximal end,
a cartridge adapted and arranged to contain at least one dose of a drug, a bung being movably arranged within the cartridge, wherein in an initial state of the device, the bung is arranged in a proximal end position with respect to the cartridge,
a piston rod adapted and arranged to move the bung in the distal direction with respect to the cartridge for delivering a dose of the drug,
wherein the device comprises a mechanism operable such that, after a dose delivery operation is completed, the piston rod is moved into the proximal direction with respect to the bung by a back off distance (D), and wherein in the initial state, a distance between a distal end of the piston rod and a proximal end of the bung is greater than zero, with the distance between the piston rod and the bung in the initial state being defined by the back off distance (D).

2. The device according to claim 1 , further comprising an actuation member which is moveable with respect to the housing, wherein, the actuation member is moveable between a first position and a second position, and wherein movement of the actuation member for being displaced from the first position into the second position is transferred to the piston rod for displacing the piston rod by the back off distance.

3. The device according to claim 1 , wherein the back off distance (D) is greater than or equal to the distance between the distal end of the piston rod and the proximal end of the bung in the initial state.

4. The device according to claim 2 , wherein the actuation member is further moveable between the second position and a third position, in which the actuation member is positioned after a dose setting operation is completed, wherein the third position is arranged more proximally with respect to the housing than the second position.

5. The device according to claim 2 , comprising a spring member which is mounted within the housing, wherein the spring member is configured and arranged to exert a force onto the actuation member to move the actuation member from the first position into the second position, thereby moving the piston rod proximally by the back off distance (D).

6. The device according to claim 5 , wherein the back off distance (D) is in the range of 0.1 to 1.0 mm.

7. The device according to claim 5 , wherein the back off distance (D) is less than the distance by which the piston rod is moved distally during a dose delivery operation.

8. The device according to claim 1 , wherein the piston rod is configured such that the axial dimension of the piston rod can be varied.

Assignees

• Sanofi Aventis Deutschland

Inventors

• Helmer Michael
• Eisengarthen Christoph
• Huthmacher Winfried
• Mosebach Carsten

Classifications

• Y10T29/4978

  Assisting assembly or disassembly · CPC title

• A61M5/31511

  Piston or piston-rod constructions, e.g. connection of piston with piston-rod (A61M5/5066 takes precedence) · CPC title

• A61M5/24 Primary

  Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic {(ampoules or carpules A61J1/06)} · CPC title

• A61M2005/3103

  Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle · CPC title

• A61M2207/00

  Methods of manufacture, assembly or production · CPC title