Novel tetrazolone derivatives
US-2016083357-A1 · Mar 24, 2016 · US
Tetrazolones as a carboxylic acid bioisosteres
US9701647B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9701647-B2 |
| Application number | US-201615233676-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 10, 2016 |
| Priority date | Jan 26, 2015 |
| Publication date | Jul 11, 2017 |
| Grant date | Jul 11, 2017 |
How to read this patent
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
- Title
What the patent document calls the invention.
- Abstract
A short plain-language summary of the technical disclosure.
- Assignees and inventors
Who owns or filed the patent and who is credited as inventor.
- Key dates
Filing, priority, publication, and grant dates set the timeline.
- First independent claim
The legal scope of protection — read this for what is actually claimed.
- CPC / IPC classifications
Technology tags used to group this patent with similar filings.
- Citations and related patents
Prior art links and similar publications in this corpus.
Abstract
Official abstract text for this publication.
The present disclosure provides compounds that include a tetrazolone derivative of a carboxyl group of an active agent. This disclosure also relates to pharmaceutical compositions that include these compounds, methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.
First claim
Opening claim text (preview).
What is claimed is: 1. A method of treating a disease or disorder in a subject in need of treatment, the method comprising administering to the subject a compound comprising a tetrazolone derivative of a carboxyl group of an active agent wherein said compound is of formula: wherein R1 is the active agent; and R2 is selected from hydrogen, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, heteroaryl, and substituted heteroaryl; or a salt or stereoisomer thereof. 2. The method of claim 1 , wherein R 2 is hydrogen or alkyl. 3. A The method of claim 1 , wherein the active agent is a therapeutically effective active agent. 4. The method of claim 1 , wherein the tetrazolone derivative is produced from the carboxyl group of the active agent. 5. The method of claim 1 , wherein the compound is selected from:
Assignees
Inventors
Classifications
Antianaemics · CPC title
Antihypertensives · CPC title
Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title
for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis · CPC title
for hyperglycaemia, e.g. antidiabetics · CPC title
Patent family
Related publications grouped by family.
External sources
Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US9701647B2 cover?
- The present disclosure provides compounds that include a tetrazolone derivative of a carboxyl group of an active agent. This disclosure also relates to pharmaceutical compositions that include these compounds, methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.
- Who is the assignee on this patent?
- Rigel Pharmaceuticals Inc
- What technology area does this patent fall under?
- Primary CPC classification C07D257/04. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jul 11 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).