Filtration system for preparation of fluids for medical applications

Patent metadata

Field	Value
Publication number	US-9700663-B2
Application number	US-81347206-A
Country	US
Kind code	B2
Filing date	Jan 9, 2006
Priority date	Jan 7, 2005
Publication date	Jul 11, 2017
Grant date	Jul 11, 2017

Abstract

Systems, methods, and devices for preparation of water for various uses including blood treatment are described. In embodiments, fluid is passed either by pump or passively by gravity feed, through various filtration elements from a fluid source to a treatment fluid container. The latter forms a batch that may be used during treatment. Methods and systems for creating multiple-treatment batches are described. Advantages of creating a multitreatment batch include the fact that the burden of treatment preparation can be reduced and the timing of the preparation of the batch can be independent of the treatment time. As described, there are various trade-offs and concerns with this approach which are addressed by the inventive embodiments.

First claim

What is claimed is:

1. A medical fluid treatment device in combination with a renal replacement therapy device, the medical fluid treatment device comprising:
a housing having water supply and drain connections and an electrical supply connection;
a treatment fluid preparation device configured to purify water and to dilute a solute or concentrate with the purified water so as to prepare a batch of treatment fluid;
said batch of treatment fluid being contained in a disposable bag supported by a support enclosed in said housing;
said batch containing enough treatment fluid to perform multiple renal replacement therapy treatments each being at least a day apart;
a heater arranged on the support and configured to heat the batch of treatment fluid so as to maintain a temperature of said batch of treatment fluid in the disposable bag at a temperature for immediate use in renal replacement therapy;
a controller configured to indicate at least one of: an indication that said batch has expired, an indication that said batch is about to expire, and an amount of time before said batch will expire;
said controller having an output connected to the heater and an input connected to a temperature sensor, which monitors the temperature of said batch of treatment fluid in said bag,
the controller being configured to maintain the batch of treatment fluid in the disposable bag at said temperature for immediate use in renal replacement therapy while allowing consumption of said batch over multiple treatments by controlling the heater to heat the batch of treatment fluid in response to a signal from the temperature sensor; and
connections connecting the renal replacement therapy device to receive contents of said disposable bag.

2. A device as in claim 1 , wherein said support includes a tank portion configured to support said bag.

3. A device as in claim 1 , wherein said bag includes a first filter that is replaced each time said bag is replaced.

4. A device as in claim 1 , wherein said housing has a table top surface and said table top is configured to support said renal replacement therapy device.

5. A device as in claim 1 , wherein said housing has a table top surface and a height not greater than 1 m.

6. A device as in claim 1 , wherein said treatment fluid preparation device includes a disposable filtration module that is replaced once every multiple batches.

7. A device as in claim 1 , wherein said support includes a tank portion configured to support said bag, said tank portion being configured as a drawer portion that is hidden behind a door on a front of said housing.

8. A device as in claim 1 , wherein:
said housing has a table top surface and a height not greater than 1 m.;
said table top is uninterrupted by any fixtures;
said controller has a user interface mounted on a front of said housing.

9. A device as in claim 1 , wherein said housing has a table top surface and a height not greater than 75 cm.

10. A device as in claim 1 , wherein said disposable bag has multiple outlet connections, each configured with a non-reopenable clamp.

11. A device as in claim 1 , wherein said treatment fluid includes a lactate based dialysate.

12. A device as in claim 1 , wherein said housing is fitted with wheels.

13. A device as in claim 1 , wherein said support includes a recess portion configured to support said bag, said recess having a bottom on which said bag sits, said bottom being at a bottom of said housing and having at least one leak sensor therein.

14. A device as in claim 1 , wherein said housing has at least one leak sensor outside of any fluid containing or conveying component to detect leaks.

15. A device as in claim 1 , wherein said controller is configured to empty said bag after use.

16. A device as in claim 1 , further comprising a drain connection, which includes a Y-junction receiving a connection from said disposable bag and a connector for connection to a spent fluid line of said renal replacement therapy device.

17. A device as in claim 16 , wherein one leg of said Y-junction includes a conductivity sensor configured to allow said controller to test a sample of said batch by flushing a portion thereof into said Y-junction.

18. A device as in claim 1 , wherein said disposable bag includes an actuator portion with a filter that is replaced for each batch.

19. A medical fluid treatment device in combination with a renal replacement therapy device, the medical fluid treatment device comprising:
a housing having water supply and drain connections and an electrical supply connection;
a treatment fluid preparation device configured to purify water and to dilute a solute or concentrate with the purified water so as to prepare a batch of treatment fluid;
said batch of treatment fluid being contained in a disposable bag supported by a support enclosed in said housing;
said batch containing enough treatment fluid to perform multiple renal replacement therapy treatments each being at least a day apart;
a heater arranged on the support and configured to heat the batch of treatment fluid so as to maintain a temperature of said batch of treatment fluid in the disposable bag at a temperature for immediate use in renal replacement therapy;
a controller configured to indicate at least one of: an indication that said batch has expired, an indication that said batch is about to expire, and an amount of time before said batch will expire;
said controller having an output connected to the heater and an input connected to a temperature sensor, which monitors the temperature of said batch of treatment fluid in said bag,
the controller being configured to maintain the batch of treatment fluid in the disposable bag at said temperature for immediate use in renal replacement therapy while allowing consumption of said batch over multiple treatments by controlling the heater to heat the batch of treatment fluid in response to a signal from the temperature sensor; and
connections connecting the renal replacement therapy device to receive contents of said disposable bag,
wherein said disposable bag includes an actuator portion with a first filter that is replaced for each batch, and
wherein said treatment fluid preparation device includes a second filter that is replaced once every multiple batches.

20. A device as in claim 1 , further comprising a pump and fluid circuit portion configured to generate a constant pressure for uptake by said renal replacement therapy device.

21. A medical fluid treatment device in combination with a renal replacement therapy device, the medical fluid treatment device comprising:
a housing having water supply and drain connections and an electrical supply connection;
a treatment fluid preparation device configured to purify water and to dilute a solute or concentrate with the purified water so as to prepare a batch of treatment fluid;
said batch of treatment fluid being contained in a disposable bag supported by a support enclosed in said housing;
said batch containing enough treatment fluid to perform multiple renal replacement therapy treatments each being at least a day apart;
a heater arranged on the support and configured to heat the batch of treatment fluid so as to maintain a temperature of said batch of treatment fluid in the disposable bag at a temperature for immediate use in renal replacement therapy;
a controller configured to indicate at least one of: an indication that said batch has expired, an indication that said batch is about to expire, and an amou

Assignees

• Burbank Jeffrey H
• Treu Dennis M
• Friederichs Götz
• Green Brian C
• Mcdowell Christopher S
• Brugger James M
• Nxstage Medical Inc

Inventors

• Burbank Jeffrey H
• Treu Dennis M
• Friederichs Götz
• Green Brian C
• Mcdowell Christopher S
• Brugger James M

Classifications

• A61M1/288

  Priming (priming in extracorporeal blood circuits A61M1/3643) · CPC title

• A61M2205/12

  with interchangeable cassettes forming partially or totally the fluid circuit · CPC title

• A61M1/1668

  Details of containers · CPC title

• A61M1/1656 Primary

  Apparatus for preparing dialysates · CPC title

• A61M1/167

  Flexible packaging for solid concentrates · CPC title