Magnetic resonance imaging apparatus and magnetic resonance imaging method

Patent metadata

Field	Value
Publication number	US-9700220-B2
Application number	US-79048407-A
Country	US
Kind code	B2
Filing date	Apr 25, 2007
Priority date	Apr 25, 2006
Publication date	Jul 11, 2017
Grant date	Jul 11, 2017

Abstract

A magnetic resonance imaging apparatus includes an imaging condition setting unit, a scan performing unit and a blood flow image generating unit. The imaging condition setting unit sets a sequence accompanying application of a motion probing gradient pulse as an imaging condition. The scan performing unit performs an imaging scan according to the sequence. The blood flow image generating unit generates a blood flow image based on data acquired by the imaging scan.

First claim

What is claimed is:

1. A magnetic resonance imaging (MRI) apparatus comprising:
an MRI sequence controller configured to perform an imaging sequence wherein imaging data is acquired after performing a pre-pulse sequence which applies a gradient magnetic field pulse for flow selection to perform one of (a) compensating a flow and (b) facilitating flow void effect in a blood vessel of an object, said imaging data being acquired by performing an MRI pulse sequence which includes a radio frequency excitation pulse and which is independent from a blood travel direction of a target blood vessel; and
a blood flow image generating unit configured to generate a non-contrast-enhanced blood flow image of the object based on magnetic resonance signals acquired by the imaging sequence,
wherein the MRI sequence controller is configured to control the pre-pulse sequence so that (a) the gradient magnetic field pulse for flow selection in the pre-pulse sequence is applied in a blood flow travel direction of the target blood vessel, and (b) a longitudinal magnetization recovery pulse in the pre-pulse sequence is applied after the gradient magnetic field pulse for flow selection is applied, the longitudinal magnetization recovery pulse transforming transverse magnetization of spins into longitudinal magnetization.

2. A magnetic resonance imaging apparatus according to claim 1 , wherein
said MRI sequence controller is configured to apply the longitudinal magnetization recovery pulse previous to performing the MRI pulse sequence that is independent from the blood travel direction of the target blood vessel.

3. A magnetic resonance imaging apparatus according to claim 1 , wherein
said MRI sequence controller is configured to acquire a first echo signal set by performing a first three dimensional scan at a first cardiac time phase of the object and a second echo signal set by performing a second three dimensional scan at a second cardiac time phase of the object, at least one of the first and the second three dimensional scans being performed during said MRI pulse sequence and thus subsequent to applying the gradient magnetic field pulse for flow selection during the pre-pulse sequence, and
said blood flow image generating unit is configured to generate a subtraction image by subtraction between a first image and a second image, the first and the second images being generated based on the first and the second echo signal sets, respectively.

4. A magnetic resonance imaging apparatus according to claim 1 , wherein
said MRI sequence controller is configured to apply a pre-pulse serving as the gradient magnetic field pulse for the flow selection to either of (a) a blood flow in an artery and (b) a blood flow having a fast flow velocity.

5. A magnetic resonance imaging apparatus according to claim 1 , wherein
said MRI sequence controller is configured to apply a motion probing gradient pulse as the gradient magnetic field pulse for flow selection.

6. A magnetic resonance imaging apparatus according to claim 1 , wherein
said MRI sequence controller is configured to use during said MRI pulse sequence either of (a) a sequence for aligning a phase of a transverse magnetization in every repeated excitation and (b) a balanced SSFP sequence for acquiring signals in a state of Steady State Free Precession as the sequence independent from the blood travel direction of the target blood vessel.

7. A magnetic resonance imaging apparatus according to claim 1 , further comprising:
said MRI sequence controller being configured to perform a preparation scan with intensities of plural types of gradient magnetic field pulses for flow selections; and
a reference blood flow image generating unit configured to generate blood flow images for reference based on data corresponding to each intensity of the plural types of the gradient magnetic field pulses for the flow selections, the data being acquired by the preparation scan,
wherein said MRI sequence controller is configured to perform the pre-pulse sequence with an intensity of a gradient magnetic field pulse for a flow selection used for a preparation scan for a reference blood flow image selected from the blood flow images for the reference.

8. A magnetic resonance imaging apparatus according to claim 3 , wherein
said MRI sequence controller is configured to acquire MRI data in a vicinity of a center of k-space during diastole serving as the first cardiac time phase and during systole as the second cardiac time phase.

9. A magnetic resonance imaging apparatus according to claim 5 , further comprising
an imaging condition setting unit configured to be able to change intensities of the motion probing gradient pulse in three directions of a gradient magnetic field direction for slice encoding, a gradient magnetic field direction for phase encoding and a gradient magnetic field direction for readout.

10. A magnetic resonance imaging apparatus according to claim 9 , wherein
said imaging condition setting unit is configured to be able to change the intensities of the motion probing gradient pulse in accordance with the blood travel direction of the target blood vessel.

11. A magnetic resonance imaging apparatus according to claim 1 , wherein
said MRI sequence controller is configured to use an MRI pulse sequence according to a PROPELLER method for filling k-space by acquiring mutually parallel data groups forming a blade in one repetition time and rotating the blade every repetition time as the sequence independent from the blood travel direction of the target blood vessel.

12. A magnetic resonance imaging apparatus according to claim 1 , wherein
said MRI sequence controller is configured to apply the gradient magnetic field pulse for flow selection subsequent to applying an excitation pulse and previous to applying a refocus pulse.

13. A magnetic resonance imaging apparatus comprising:
an MRI sequence controller configured to perform an imaging sequence wherein imaging data is acquired after performing a pre-pulse sequence which applies a gradient magnetic field pulse for flow selection to serve one of (a) a purpose of compensating a flow and (b) another purpose of facilitating flow void effect in a blood vessel of an object, said imaging data being acquired by performing an MRI pulse sequence which includes a radio frequency excitation pulse and which is independent from a blood travel direction of a target blood vessel; and
a blood flow image generating unit configured to generate a non-contrast-enhanced blood flow image of the object based on magnetic resonance signals acquired by the imaging sequence,
wherein the MRI sequence controller is configured to control the pre-pulse sequence so as to include a longitudinal magnetization recovery pulse that transforms a transverse magnetization of spins into a longitudinal magnetization and is applied after application of the gradient magnetic field pulse for flow selection.

14. A magnetic resonance imaging (MRI) apparatus comprising:
an MRI sequence controller configured to perform an imaging sequence wherein imaging data is acquired after performing a pre-pulse sequence which applies a gradient magnetic field pulse for flow selection to perform one of (a) compensating a flow and (b) facilitating flow void effect in a blood vessel of an object, said imaging data being acquired by performing an MRI pulse sequence which includes a radio frequency excitation pulse and which is independent from a blood travel direction of a target blood vessel; and
a blood flow image generating unit configured to generate a non-contrast-enhanced blood flow image of the object based on mag

Assignees

• Miyazaki Mitsue
• Kanazawa Hitoshi
• Toshiba Medical Sys Corp

Inventors

• Miyazaki Mitsue
• Kanazawa Hitoshi

Classifications

• G01R33/5617

  using RF refocusing, e.g. RARE · CPC title

• G01R33/4824

  using a non-Cartesian trajectory · CPC title

• G01R33/5635

  Angiography, e.g. contrast-enhanced angiography [CE-MRA] or time-of-flight angiography [TOF-MRA] · CPC title

• G01R33/4818

  MR characterised by data acquisition along a specific k-space trajectory or by the temporal order of k-space coverage, e.g. centric or segmented coverage of k-space · CPC title

• G01R33/56509

  due to motion, displacement or flow, e.g. gradient moment nulling (G01R33/567 takes precedence) · CPC title