Eye mounted device for therapeutic agent release
US-12167978-B2 · Dec 17, 2024 · US
US9694180B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9694180-B2 |
| Application number | US-201113097516-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 29, 2011 |
| Priority date | Apr 30, 2010 |
| Publication date | Jul 4, 2017 |
| Grant date | Jul 4, 2017 |
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A method of testing subjects' perception of complex shapes created by patterned multi-electrode direct stimulation of a retinal prosthesis is described. The complex shapes can be geometric shapes or characters such as letters of the alphabet and numbers.
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The invention claimed is: 1. A method, comprising: providing a visual prosthesis a portion of which is adapted to be implanted in a subject, the visual prosthesis comprising a video processor and an array of electrodes; selecting and defining a first set of geometric shapes; selecting and defining a second set of geometric shapes; displaying a geometric shape from the first set of geometric shapes to the subject, wherein the displaying is by stimulating a plurality of electrodes in a multi-electrode pattern within the array of electrodes corresponding to the geometric shape; recording a drawing by the subject on an electronic input device of the geometric shape perceived by the subject, thus creating a described shape; comparing the described shape to geometric shapes from the second set of geometric shapes and determining a selected shape in the second set of geometric shapes closest to the described shape using an automatic tool; and adjusting the visual prosthesis based on the comparing of the described shape and the selected shape, thus performing spatial fitting for the visual prosthesis; wherein the steps of selecting, comparing, recording and adjusting are by autonomous processes in the video processor. 2. The method according to claim 1 , wherein the stimulating of electrodes is by frequency encoding. 3. The method according to claim 1 , wherein the stimulating of electrodes is by amplitude encoding. 4. A visual prosthesis, comprising: a control device adapted for selecting and defining a first set of geometric shapes, a second set of geometric shapes and a third set of geometric shapes; an array of electrodes configured for placement in proximity of a visual neural tissue of a subject; a neural stimulator, coupled to the control device and the array of electrodes, adapted for applying stimuli to the visual neural tissue of the subject to elicit percepts and adapted for displaying a geometric shape from the first set of geometric shapes to the subject, wherein the displaying is by stimulating a plurality of electrodes in a multi-electrode pattern within the array of electrodes corresponding to the geometric shape; and means for recording a drawing by the subject of the geometric shape perceived by the subject on an electronic input device, thus creating a described shape, wherein the control device is further adapted for: comparing the described shape to geometric shapes from a second set of geometric shapes and selecting a selected shape from the second set of geometric shapes closest to the described shape, and adjusting the selection of electrodes to be stimulated in the array of electrodes corresponding to a geometric shape from a third set of geometric shapes based on the comparing, thus improving spatial fitting for perceived image of the visual prosthesis. 5. The method according to claim 4 wherein the first set of geometric shapes and the second set of geometric shapes are the same.
of the eye · CPC title
Retinal electrodes · CPC title
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