Powderous formulations of organic acids or esters having an aromatic ring system

Patent metadata

Field	Value
Publication number	US-9693938-B2
Application number	US-201414907656-A
Country	US
Kind code	B2
Filing date	Jul 25, 2014
Priority date	Jul 26, 2013
Publication date	Jul 4, 2017
Grant date	Jul 4, 2017

Abstract

The present invention relates to improved powderous formulations comprising a high amount of at least one organic acids or esters having an aromatic ring system, as well as to the production of such formulations.

First claim

The invention claimed is:

1. A powderous formulation comprising
(i) 70-95 wt %, based on the total weight of the powderous formulation, of at least one compound of formula (I):

 wherein
X is —N— or —CH—, and
R 1 is H or a C 1 -C 4 alkyl moiety, and

(ii) 10-30 wt %, based on the total weight of the powderous formulation, of at least one auxiliary compound selected from the group consisting of ammonium dihydrogen phosphate, purified diatomaceous earth, potassium hydrogen carbonate, potassium sulphate, potassium carbonate, sodium chloride and sodium hydrogen carbonate, wherein
the powderous formulation has minimum ignition energy (MIE) value of 10 mJ or greater.

2. The powderous formulation according to claim 1 , wherein the at least one compound of formula (I) is at least one compound of formula (Ia) and (Ib):

3. The powderous formulation according to claim 1 , wherein the auxiliary compounds have an average particle size (d 0.5) in the powder formulation of 10 μm-100 μm.

4. The powderous formulation according to claim 1 , wherein the compounds of formula (I) is present in an amount sufficient to impart a MIE value to the formulation of 10-1000 mJ.

5. The powderous formulation according to claim 1 , wherein the compounds of formula (I) is present in an amount sufficient to impart a MIE value to the formulation of more than 1000 mJ.

6. The powderous formulation according to claim 1 , comprising 0-5 wt-%, based on the total weight of the formulation, of water.

7. A powderous formulation according to claim 1 , wherein the formulation further comprises:
(iii) up to 40 wt-%, based on the total weight of the formulation, of at least one carrier material selected from the group consisting of synthetically produced precipitated silicas, formiates, proteins, starches, lignosulfonates and gums.

8. A powderous formulation consisting of:
(i) 70-90 wt-%, based on the total weight of the powderous formulation, of at least one compound of formula (Ia) and (Ib):

 and
(ii) 10-30 wt-%, based on the total weight of the powderous formulation, of at least one auxiliary compound selected from the group consisting of ammonium dihydrogen phosphate, diatomaceous earth, potassium hydrogen carbonate, potassium sulphate, potassium carbonate, sodium chloride, sodium sulphate and sodium hydrogen carbonate, and
(iii) 0-5 wt-%, based on the total weight of the powderous formulation, of water, wherein
the powderous formulation has a minimum ignition energy (MIE) value of 10 mJ or greater.

9. A food product, feed product or personal care product comprising the powderous formulation according to claim 1 .

Assignees

• Dsm Ip Assets Bv

Inventors

• Gadient Martin
• Aeschlimann Marie Agnes
• Isner Romeo

Classifications

• A61K9/14

  Particulate form, e.g. powders, {Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles (microspheres A61K9/16; microcapsules A61K9/50; nanocapsules, nanoparticles of the matrix type A61K9/51)} · CPC title

• A61K8/36

  Carboxylic acids; Salts or anhydrides thereof · CPC title

• A61K8/0241

  Containing particulates characterized by their shape and/or structure (see also A61K8/04, A61K8/11, and A61K8/14, further aspects are classified in A61K2800/40 and subcodes) · CPC title

• A23P10/40

  free-flowing powder or instant powder, i.e. powder which is reconstituted rapidly when liquid is added (A23P10/20, A23P10/30 take precedence) · CPC title

• A23L33/15

  Vitamins · CPC title