Column contained in container and column container

Patent metadata

Field	Value
Publication number	US-9689848-B2
Application number	US-201415026175-A
Country	US
Kind code	B2
Filing date	Sep 30, 2014
Priority date	Sep 30, 2013
Publication date	Jun 27, 2017
Grant date	Jun 27, 2017

Abstract

Provided is a chromatography column stored in a storage container. The storage container for the column includes: a container body for storing the chromatography column; and a cover threadedly engaging with the container body. A groove for threaded engagement with the cover is formed in an inner wall of the container body. Sealing members are arranged on an inner bottom surface of the container body and a lower surface of the cover, respectively. When the container body and the cover are threadedly engaged with each other, the cover enters the container body to cause the sealing members on the inner bottom surface of the container body and the lower surface of the cover to press both a lower surface and an upper surface of the column, to thereby fix the column inside the container body and seal a fluid passage hole of the column.

First claim

The invention claimed is:

1. An article, comprising:
a storage container comprising a container body, a cover threadedly engagable with the container body, and sealing members positioned on an inner bottom surface of the container body and a lower surface of the cover, respectively; and
a chromatography column having fluid passage holes on a lower surface and an upper surface, respectively, and configured to be stored in the container body of the storage container,
wherein
the container body has a groove formed in an inner wall of the container body and configured to threadedly engage the container body and the cover such that
at least a part of the cover enters the container body, that the sealing member on the inner bottom surface of the container body presses the lower surface of the chromatography column and the sealing member on the lower surface of the cover presses the upper surface of the chromatography column to fix the chromatography column inside the container body, and that the fluid passage holes of the chromatography column are sealed.

2. The article of claim 1 , wherein the container body has a tubular shape having a minimum inner diameter of from 101% to 125% of an outer diameter of the chromatography column.

3. The article of claim 1 , wherein each of the sealing members comprises a flat plate or an O-ring formed of a material having high friction and elasticity.

4. The article of claim 1 , wherein the storage container is self-standable.

5. A storage container, comprising:
a container body configured to store a chromatography column therein;
a cover threadedly engagable with the container body; and
sealing members positioned on an inner bottom surface of the container body and a lower surface of the cover, respectively,
wherein
the container body has a groove formed in an inner wall of the container body and configured to threadedly engage the container body and the cover such that
at least a part of the cover enters the container body, that the sealing member on the inner bottom surface of the container body presses a lower surface of the chromatography column and the sealing member on the lower surface of the cover presses an upper surface of the chromatography column to fix the chromatography column inside the container body, and that fluid passage holes of the chromatography column formed on respective one of the lower surface and the upper surface of the chromatography column are sealed.

6. The storage container of claim 5 , wherein the container body has a tubular shape having a minimum inner diameter of from 101% to 125% of an outer diameter of the chromatography column.

7. The storage container of claim 5 , wherein each of the sealing members comprises a flat plate or an O-ring formed of a material having high friction and elasticity.

8. The storage container of claim 5 , wherein the storage container is self-standable.

9. The article of claim 1 , wherein the sealing members comprise a flat plate, and the groove of the container is configured to threadedly engage the container body and the cover such that the fluid passage holes of chromatography column are sealed by the flat plate.

10. The article of claim 1 , wherein the sealing members comprise an O-ring, and the groove of the container is configured to threadedly engage the container body and the cover such that the fluid passage holes of chromatography column are sealed by the O-ring and one of the bottom surface of the container body and the lower surface of the cover.

11. The article of claim 1 , wherein the sealing members have a thickness of from about 0.3 mm to 3.0 mm.

12. The article of claim 1 , wherein at least a part of the container body or the cover is in a polygonal column shape.

13. The article of claim 1 , wherein the sealing members comprise at least one of an elastomer, a synthetic rubber, and a natural rubber.

14. The article of claim 1 , wherein each of the sealing members comprises a flat plate having a diameter larger than a diameter of the fluid passage holes of the chromatography column, or an O-ring having an outer diameter larger than the diameter of the fluid passage holes of the chromatography column.

15. The storage container of claim 5 , wherein the sealing members comprise a flat plate, and the groove of the container is configured to threadedly engage the container body and the cover such that the fluid passage holes of chromatography column are sealed by the flat plate.

16. The storage container of claim 5 , wherein the sealing members comprise an O-ring, and the groove of the container is configured to threadedly engage the container body and the cover such that the fluid passage holes of chromatography column are sealed by the O-ring and one of the bottom surface of the container body and the lower surface of the cover.

17. The storage container of claim 5 , wherein the sealing members have a thickness of from about 0.3 mm to 3.0 mm.

18. The storage container of claim 5 , wherein at least a part of the container body or the cover is in a polygonal column shape.

19. The storage container of claim 5 , wherein the sealing members comprise at least one of an elastomer, a synthetic rubber, and a natural rubber.

20. The storage container of claim 5 , wherein each of the sealing members comprises a flat plate having a diameter larger than a diameter of the fluid passage holes of the chromatography column, or an O-ring having an outer diameter larger than the diameter of the fluid passage holes of the chromatography column.

Assignees

• Sekisui Medical Co Ltd

Inventors

• Yotani Takuya
• Nemoto Yuriko
• Muraki Hideki

Classifications

• G01N30/6004

  end pieces · CPC title

• B65D53/02

  Collars or rings · CPC title

• B65D41/0407

  with integral sealing means (B65D41/065 takes precedence) · CPC title

• G01N30/6047 Primary

  with supporting means; Holders · CPC title

• B01D15/20

  relating to the conditioning of the sorbent material · CPC title