Fluorescent sensors
US-2024019450-A1 · Jan 18, 2024 · US
US9688857B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9688857-B2 |
| Application number | US-201615292858-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 13, 2016 |
| Priority date | Jan 20, 2011 |
| Publication date | Jun 27, 2017 |
| Grant date | Jun 27, 2017 |
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A compound represented by the formula (I) (R 1 represents hydrogen atom or a monovalent substituent; R 2 and R 3 represent hydrogen atom, an alkyl group, or a halogen atom; R 4 and R 5 represent an alkyl group or an aryl group; R 6 and R 7 represent hydrogen atom, an alkyl group, or a halogen atom; R 8 represent hydroxy group or a dialkoxyboranetriyl group; and X represents silicon atom, germanium atom, or tin atom), which is a novel fluorophore usable as a mother nucleus of an off/on type fluorescent probe not utilizing the intramolecular photoinduced electron transfer.
Opening claim text (preview).
What is claimed is: 1. A chemical compound represented by the following general having formula (IV): wherein, in the formula, R 2 and R 3 independently represent hydrogen atom, an alkyl group having 1 to 6 carbon atoms, or a halogen atom; R 4 and R 5 independently represent an alkyl group having 1 to 6 carbon atoms, or an aryl group having 1 to 6 carbon atoms; R 6 and R 7 independently represent hydrogen atom, an alkyl group having 1 to 6 carbon atoms, or a halogen atom; R 13 represents a protective group of phenolic hydroxy group; and X represents germanium atom, or tin atom, or a salt thereof. 2. The compound according to claim 1 , wherein each of R 6 and R 7 represents a halogen atom. 3. The compound according to claim 2 , wherein each of R 2 and R 3 represents a hydrogen atom. 4. The compound according to claim 1 , wherein each of R 2 , R 3 , R 6 and R 7 represents a hydrogen atom. 5. A chemical compound having formula (IV): wherein, in the formula, R 2 and R 3 independently represent hydrogen atom, an alkyl group having 1 to 6 carbon atoms, or a halogen atom; R 4 and R 5 independently represent an alkyl group having 1 to 6 carbon atoms, or an aryl group having 1 to 6 carbon atoms; R 6 and R 7 independently represent hydrogen atom, an alkyl group having 1 to 6 carbon atoms, or a halogen atom; R 13 represents a protective group of phenolic hydroxy group; wherein at least one of R 2 , R 3 , R 6 and R 7 represents an alkyl group having 1 to 6 carbon atoms, or a halogen atom; and X represents silicon atom, germanium atom, or tin atom, or a salt thereof. 6. The compound according to claim 5 , wherein each of R 6 and R 7 represents a halogen atom. 7. The compound according to claim 6 , wherein each of R 2 and R 3 represents a hydrogen atom. 8. A chemical compound having formula (IV): wherein, in the formula, R 2 and R 3 independently represent hydrogen atom, an alkyl group having 1 to 6 carbon atoms, or a halogen atom; each of R 4 and R 5 represents an ethyl group; R 6 and R 7 independently represent hydrogen atom, an alkyl group having 1 to 6 carbon atoms, or a halogen atom; R 13 represents a protective group of phenolic hydroxy group; and X represents silicon atom, germanium atom, or tin atom, or a salt thereof. 9. The compound according to claim 8 , wherein each of R 6 and R 7 represents a halogen atom. 10. The compound according to claim 9 , wherein each of R 2 and R 3 represents a hydrogen atom. 11. The compound according to claim 8 , wherein each of R 2 , R 3 , R 6 and R 7 represents a hydrogen atom.
Germanium compounds · CPC title
with indicators, stains, dyes, tags, labels, marks · CPC title
containing nitrogen {having a Si-N linkage} · CPC title
having amino groups bound to only one six-membered aromatic ring · CPC title
said ring comprising Si as a ring atom · CPC title
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