Oral care compositions

Patent metadata

Field	Value
Publication number	US-9687427-B2
Application number	US-201514633256-A
Country	US
Kind code	B2
Filing date	Feb 27, 2015
Priority date	May 7, 2014
Publication date	Jun 27, 2017
Grant date	Jun 27, 2017

Abstract

Oral care composition comprises a stannous ion source and a thickener comprising at least 2 agents selected from the group consisting of: i) a linear sulfated polysaccharide; ii) a natural gum; iii) and a non-ionic cellulose derivative. A method for treating the oral cavity comprises administering to the oral cavity the oral care composition.

First claim

What is claimed is:

1. A phase stable oral care composition comprising:
a. from 0.01% to 5% by weight of a stannous ion source selected from the group consisting of stannous chloride, stannous fluoride, stannous acetate, stannous gluconate, stannous oxalate, stannous sulfate, stannous lactate, stannous tartrate, and combinations thereof;
b. from 0.01% to 15% by weight of a thickener comprising:
i) a linear sulfated polysaccharide;
ii) a natural gum; and
iii) a non-ionic cellulose derivative;

c. at least 30% by weight of a total water content;
d. a dental abrasive comprising silica;
wherein the composition has a pH between 4 to 10;
wherein the composition is substantially free of carboxymethyl cellulose (CMC); and
wherein the composition is a dentifrice.

2. The oral care composition according to claim 1 , wherein the stannous ion comprises stannous chloride.

3. The oral care composition according to claim 1 , wherein the linear sulfated polysaccharide comprises carrageenan.

4. The oral care composition according to claim 3 , wherein the carrageenan is selected from the group consisting of Kappa-carrageenan, Iota-carrageenan, Lambda-carrageenan, and combinations thereof.

5. The oral care composition according to claim 1 , wherein the natural gum is selected from the group consisting of xanthan gum, gum karaya, gum arabic, gum tragacanth, and combinations thereof.

6. The oral care composition according to claim 1 , wherein the non-ionic cellulose derivative comprises an average molecular weight range of 90,000 g/mol to 1,300,000 g/mol and an average degree of polymerization from 300 to 4,800.

7. The oral care composition according to claim 6 , wherein the non-ionic cellulose derivative comprises hydroxyethyl cellulose (HEC).

8. The oral care composition according to any preceding claim, wherein the pH is between 5 and 7.

9. The oral care composition according to claim 1 , wherein the total water content is between 30% to 70% by weight.

10. The oral care composition according to claim 1 , wherein the composition is substantially free of charged cellulose derivatives having greater than 0.5 charged groups per sugar residue unit along the polysaccharide backbone.

11. The oral care composition according to claim 1 having a Tip Viscosity of greater than 100 Pa·s after 5 months at 40° C.

12. A phase stable oral care composition comprising:
a. from 0.1% to 2% by weight of a stannous ion source selected from the group consisting of stannous chloride, stannous fluoride, and combinations thereof;
b. from 0.75% to 2% by weight of a thickener comprising:
i) carrageenan;
ii) xanthan gum; and
iii) hydroxyethyl cellulose (HEC); and

c. from 40% to 60% by weight of a total water content;
d. a dental abrasive comprising silica;
wherein the composition has a pH between 5.0 to 7.0;
wherein the composition is substantially free of carboxymethyl cellulose (CMC); and
wherein the composition is a dentifrice.

13. A method for treating the oral cavity comprising administering to the oral cavity an oral care composition according to claim 12 .

14. The composition of claim 2 wherein the stannous ion source comprises stannous chloride.

15. The composition of claim 4 wherein the carrageenan is Iota-carrageenan.

16. The oral care composition according to claim 12 wherein the composition does not exhibit a substantial decrease in Tip Viscosity after 4 months at ambient conditions.

17. The oral care composition according to claim 12 wherein the composition does not exhibit a substantial decrease in Tip Viscosity after 12 months at ambient conditions.

18. The oral care composition according to claim 12 wherein the composition does not exhibit a substantial decrease in Tip Viscosity after 24 months at ambient conditions.

Assignees

• Procter & Gamble

Inventors

• Li Xiaoxiao
• Li Yujun
• Strand Ross
• Xu Xiujun

Classifications

• A61Q11/00 Primary

  Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses · CPC title

• A61K8/73

  Polysaccharides · CPC title

• A61K8/731

  Cellulose; Quaternized cellulose derivatives · CPC title

• A61K8/20

  Halogens; Compounds thereof · CPC title

• A61K8/19 Primary

  containing inorganic ingredients · CPC title