Efficient method for nuclear reprogramming

US9683232B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9683232-B2
Application numberUS-37956409-A
CountryUS
Kind codeB2
Filing dateFeb 25, 2009
Priority dateDec 10, 2007
Publication dateJun 20, 2017
Grant dateJun 20, 2017

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Abstract

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This relates to a method of preparing induced pluripotent stem cells, comprising a nuclear reprogramming step with a nuclear reprogramming factor in the presence of miRNA, wherein said miRNA has a property of providing a higher nuclear reprogramming efficiency in the presence of said miRNA than in the absence thereof.

First claim

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What is claimed is: 1. A method of preparing an induced pluripotent stem cell from a mammalian somatic cell, comprising nuclear reprogramming the mammalian somatic cell under culture conditions which allow for mammalian somatic cell reprogramming to pluripotency with at least one miRNA and an expression vector encoding at least one nuclear reprogramming factor, wherein the at least one miRNA increases efficiency of the nuclear reprogramming of the mammalian somatic cell compared t…

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What does patent US9683232B2 cover?
This relates to a method of preparing induced pluripotent stem cells, comprising a nuclear reprogramming step with a nuclear reprogramming factor in the presence of miRNA, wherein said miRNA has a property of providing a higher nuclear reprogramming efficiency in the presence of said miRNA than in the absence thereof.
Who is the assignee on this patent?
Yamanaka Shinya, Koyanagi Michiyo, Univ Kyoto
What technology area does this patent fall under?
Primary CPC classification C12N15/113. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Jun 20 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).