Methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries

US9683028B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9683028-B2
Application numberUS-201414557171-A
CountryUS
Kind codeB2
Filing dateDec 1, 2014
Priority dateApr 17, 2000
Publication dateJun 20, 2017
Grant dateJun 20, 2017

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Abstract

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Methods useful in constructing libraries that collectively display and/or express members of diverse families of peptides, polypeptides or proteins and the libraries produced using those methods. Methods of screening those libraries and the peptides, polypeptides or proteins identified by such screens.

First claim

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We claim: 1. A vector comprising: (i) a DNA sequence encoding an antibody variable region linked to a fragment of a wild-type pIII anchor, which does not mediate infection of phage particles; and (ii) a wild-type gene III; wherein the nucleic acid sequence encoding the fragment of the wild-type pIII anchor in (i) differs from the portion of the wild-type gene III encoding the same fragment to an extent sufficient to reduce homologous recombination between the nucleic acid encoding…

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What does patent US9683028B2 cover?
Methods useful in constructing libraries that collectively display and/or express members of diverse families of peptides, polypeptides or proteins and the libraries produced using those methods. Methods of screening those libraries and the peptides, polypeptides or proteins identified by such screens.
Who is the assignee on this patent?
Dyax Corp
What technology area does this patent fall under?
Primary CPC classification C07K16/005. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Jun 20 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).