Triphenyl monomers suitable for microstructured optical films
US-9221743-B2 · Dec 29, 2015 · US
Series of skin-whitening (lightening) compounds
US9682910B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9682910-B2 |
| Application number | US-201514750873-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 25, 2015 |
| Priority date | Jul 21, 2008 |
| Publication date | Jun 20, 2017 |
| Grant date | Jun 20, 2017 |
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- Title
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Abstract
Official abstract text for this publication.
The present invention is directed to inhibitors of tyrosinase, pharmaceutical compositions comprising such tyrosinase inhibitors, and methods of making and using the same. Specifically, included in the present invention are compositions of matter comprised of at least one 2,4-dihydroxybenzene analog, which inhibit the activity of tyrosinase and which inhibit the overproduction of melanin.
First claim
Opening claim text (preview).
The invention claimed is: 1. A compound selected from 4′-methoxybiphenyl-2,4-diol, and 4-(4′-hydroxybiphenyl)benzene-1,3-diol. 2. A method for preventing and treating diseases and conditions related to the overproduction or uneven distribution of melanin comprising administering to a subject in need thereof an effective amount of a composition comprising one or more compounds selected from the group consisting of 4′-methoxybiphenyl-2,4-diol, and 4-(4′-hydroxybiphenyl)benzene-1,3-diol. 3. The method of claim 2 , wherein the diseases and conditions are selected from the group consisting of damage resulting from exposure to the sun or ultraviolet (UV) radiation, suntan, hyper pigmentation spots caused by skin aging, melasma, liver diseases, thermal burns and topical wounds, skin pigmentation due to inflammatory conditions cased by fungal, microbial and viral infections, vitilago, carcinoma, melanoma. 4. A composition comprising the compound of claim 1 and a pharmaceutically or cosmetically acceptable carrier. 5. A method of inhibiting the browning or color changes in fruits, vegetables, juices and other fruit products by administering a composition comprising the compound of claim 1 . 6. A method of inhibiting the activity of tyrosinase in a patient by administering a composition comprising the compound of claim 1 . 7. A method of inhibiting the activity of melanin in a patient by administering a composition comprising the compound of claim 1 . 8. A method of whitening, lightening, or a combination thereof, the skin of a patient by administering a composition comprising the compound of claim 1 .
Assignees
Inventors
Classifications
Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title
Antimycotics · CPC title
Antibacterial agents · CPC title
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics · CPC title
Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] · CPC title
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- What does patent US9682910B2 cover?
- The present invention is directed to inhibitors of tyrosinase, pharmaceutical compositions comprising such tyrosinase inhibitors, and methods of making and using the same. Specifically, included in the present invention are compositions of matter comprised of at least one 2,4-dihydroxybenzene analog, which inhibit the activity of tyrosinase and which inhibit the overproduction of melanin.
- Who is the assignee on this patent?
- Unigen Inc
- What technology area does this patent fall under?
- Primary CPC classification C07C43/23. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jun 20 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).