Methods and apparatus for adaptable pressure treatment of sleep disordered breathing

Patent metadata

Field	Value
Publication number	US-9682208-B2
Application number	US-201013509880-A
Country	US
Kind code	B2
Filing date	Nov 16, 2010
Priority date	Nov 16, 2009
Publication date	Jun 20, 2017
Grant date	Jun 20, 2017

Abstract

Respiratory pressure treatment apparatus include automated methodologies for controlling changes to pressure in the presence of sleep disordered breathing events. In an example apparatus, various levels of expiratory pressure relief can provide different pressure reductions for patient comfort during expiration ( 333 -A, 333 -B, 333 -C). The control parameters for these levels may be automatically modified based on the detection of an open airway. Similarly, in some embodiments, the levels may be automatically adjusted based on a detection of persistent obstruction. In still further embodiments, control parameters associated with a rise time of an early portion of an inspiratory pressure treatment may be automatically adjusted upon detection of flow limitation to permit a change to more aggressive waveforms from more comfortable waveforms for the treatment of sleep disordered breathing events.

First claim

The invention claimed is:

1. A method of control for a respiratory pressure treatment apparatus comprising:
generating a flow of breathable gas at a patient interface with a respiratory pressure treatment apparatus, the flow of breathable gas being synchronized with a respiratory cycle, the flow of breathable gas comprising expiratory pressure portions and inspiratory pressure portions wherein an expiratory pressure portion is at a pressure lower than an inspiratory pressure portion by a level of expiratory pressure relief;
measuring a flow of breathable gas at the patient interface;
detecting obstruction to flow from the measure of flow with a controller of the respiratory treatment apparatus and successively increasing pressure of the inspiratory pressure portions in response to obstruction detections while maintaining a set level of expiratory pressure relief for the expiratory pressure portions;
detecting persistent obstruction to flow from the measure of flow with the controller of the respiratory treatment apparatus based on the successively increasing pressure of the inspiratory pressure portions; and
with the controller, modifying control parameters for at least one of the expiratory pressure portions to modify the level of expiratory pressure relief delivered during the expiratory pressure portion in response to the detection of the persistent obstruction, the modifying being a decrease in the level of expiratory pressure relief.

2. A respiratory pressure treatment apparatus comprising:
a flow generator to generate a flow of breathable gas to a patient interface;
a sensor to measure the flow of breathable gas; and
a controller to control the flow generator to deliver the flow of breathable gas at the patient interface, the flow of breathable gas being synchronized with a respiratory cycle, the flow of breathable gas comprising expiratory pressure portions and inspiratory pressure portions wherein at least one of the expiratory pressure portions is at a pressure lower than at least one of the inspiratory pressure portions by a level of expiratory pressure relief;
the controller to detect obstruction to flow from the measure of flow and to successively increase pressure of the inspiratory pressure portions in response to obstruction detections while maintaining a set level of expiratory pressure relief for the expiratory pressure portions;
the controller to detect persistent obstruction to flow from the measure of flow with the controller of the respiratory treatment apparatus based on the successively increasing pressure of the inspiratory pressure portions; and
the controller to modify control parameters for at least one of the expiratory pressure portions to modify the level of expiratory pressure relief delivered during the expiratory pressure portion in response to the detection of the persistent obstruction, the modifying being a decrease in the level of expiratory pressure relief.

3. The method of claim 1 wherein detecting obstruction to flow comprises a detection of partial obstruction or obstructive apnea.

4. The method of claim 1 wherein the modifying of the control parameters for the at least one expiratory pressure portion comprises disabling expiratory pressure relief during an expiratory phase.

5. The method of claim 1 further comprising discontinuing the modification of the control parameters of the expiratory pressure portion in response to a detection of an absence of persistent obstruction over a period of time.

6. The apparatus of claim 2 wherein the controller is configured to detect flow limitation by a detection of partial obstruction or obstructive apnea.

7. The apparatus of claim 2 wherein the controller is configured to modify the control parameters of the expiratory pressure portion as a disabling of expiratory pressure relief during an expiratory phase.

8. The apparatus of claim 2 further comprising discontinuing the modification of the control parameters of the expiratory pressure portion in response to a detection of an absence of persistent obstruction over a period of time.

9. The method of claim 1 wherein the controller determines occurrence of persistent obstruction to flow from a measure of obstruction that does not substantially change during a period of time.

10. The method of claim 9 wherein the period of time comprises a number of minutes.

11. The method of claim 9 wherein the period of time comprises a number of respiratory cycles.

12. The method of claim 1 wherein the controller determines occurrence of persistent obstruction to flow from an existence of detected obstruction despite repeated changes to a therapy pressure.

13. The method of claim 12 wherein the repeated changes to a therapy pressure comprises successive increases in treatment pressure delivered during inspiration.

14. The method of claim 13 wherein the repeated changes to a therapy pressure comprises increases in treatment pressure to a maximum pressure.

15. The apparatus of claim 2 wherein the controller is configured to determine occurrence of persistent obstruction to flow from a measure of obstruction that does not substantially change during a period of time.

16. The apparatus of claim 15 wherein the period of time comprises a plurality of minutes.

17. The apparatus of claim 15 wherein the period of time comprises a plurality of respiratory cycles.

18. The apparatus of claim 2 wherein the controller is configured to determine occurrence of persistent obstruction to flow from an existence of detected obstruction despite repeated changes to a therapy pressure.

19. The apparatus of claim 18 wherein the repeated changes to a therapy pressure comprises successive increases in treatment pressure delivered during inspiration.

20. The apparatus of claim 19 wherein the repeated changes to a therapy pressure comprises increases in treatment pressure to a maximum pressure.

21. The apparatus of claim 2 wherein the modifying of the control parameters comprises disabling expiratory pressure relief for a remainder of a treatment session.

22. The apparatus of claim 2 wherein the modifying of the control parameters comprises disabling expiratory pressure relief for a remainder of a treatment session until the apparatus is restarted for a new treatment session, the disabling of the expiratory pressure relief causing the apparatus to maintain a CPAP pressure of inspiration during expiration for the remainder of the treatment session.

23. The method of claim 1 wherein the modifying of the control parameters comprises disabling expiratory pressure relief for a remainder of a treatment session.

24. The method of claim 1 wherein the modifying of the control parameters comprises disabling expiratory pressure relief for a remainder of a treatment session until the apparatus is restarted for a new treatment session, the disabling of the expiratory pressure relief causing the apparatus to maintain a CPAP pressure of inspiration during expiration for the remainder of the treatment session.

Assignees

• Ramanan Dinesh
• Armitstead Jeffrey Peter
• Martin Dion Charles Chewe
• Resmed Ltd

Inventors

• Ramanan Dinesh
• Armitstead Jeffrey Peter
• Martin Dion Charles Chewe

Classifications

• A61M16/0069 Primary

  the speed thereof being controlled by respiratory parameters, e.g. by inhalation · CPC title

• A61M2016/0027

  pressure meter · CPC title

• A61M16/0003

  Accessories therefor, e.g. sensors, vibrators, negative pressure · CPC title

• A61M2016/003

  with a flowmeter · CPC title

• A61B5/08 Primary

  Measuring devices for evaluating the respiratory organs · CPC title