Methods for nuclear reprogramming of cells
US-2015086649-A1 · Mar 26, 2015 · US
US9682103B1 · US · B1
| Field | Value |
|---|---|
| Publication number | US-9682103-B1 |
| Application number | US-201615346580-A |
| Country | US |
| Kind code | B1 |
| Filing date | Nov 8, 2016 |
| Priority date | Mar 30, 2016 |
| Publication date | Jun 20, 2017 |
| Grant date | Jun 20, 2017 |
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A method of treating a condition of a mammal, including a human individual and an animal, by intravenously administering a therapeutically effective amount of a poly -oxygenated metal hydroxide. In some embodiments, the poly-oxygenated metal hydroxide is an aluminum poly-oxygenated hydroxide, such as Ox66™. The poly-oxygenated metal hydroxide may have particles having a diameter of less than or equal to 1 um, and specifically having a diameter of less than or equal to 100 nm. The poly-oxygenated metal hydroxide may be 75-90% colloid or crystalline solution with 10-25% addition of poly-oxygenated metal hydroxide particles.
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What is claimed is: 1. A method of treating a human individual, comprising: administering a therapeutically effective amount of a poly-oxygenated aluminum hydroxide composition to a human individual to reduce a proliferation of heptocarcinoma cells (HEPG-2), wherein the poly-oxygenated aluminum hydroxide composition comprises a clathrate containing free oxygen gas (O 2 ) molecules. 2. The method as specified in claim 1 wherein the poly-oxygenated aluminum hydroxide composition is administered intravenously. 3. The method as specified in claim 1 wherein the poly -oxygenated aluminum hydroxide composition comprises poly-oxygenated aluminum hydroxide particles having a diameter of less than or equal to 100 nm. 4. The method as specified in claim 1 wherein the poly -oxygenated aluminum hydroxide composition comprises poly-oxygenated aluminum hydroxide particles having a diameter of less than or equal to 1 um. 5. The method as specified in claim 1 wherein the poly -oxygenated aluminum hydroxide composition is a colloid solution with 10-25% addition of poly-oxygenated aluminum hydroxide. 6. The method as specified in claim 1 wherein the poly -oxygenated aluminum hydroxide composition is a crystalline solution with 10-25% addition of poly-oxygenated aluminum hydroxide. 7. The method as specified in claim 1 wherein the poly -oxygenated aluminum hydroxide composition has a concentration range of 0.1 mg/l to 1000 mg/l. 8. The method as specified in claim 1 wherein the poly -oxygenated aluminum hydroxide composition has poly-oxygenated aluminum hydroxide particles that are surface modified.
Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock (artificial tears A61P27/04) · CPC title
Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner (non-active ingredients are additionally classified in A61K47/00) · CPC title
Oxides; Hydroxides · CPC title
Blood substitute; Oxygen transporting formulations; Plasma extender · CPC title
Nanoparticle, i.e. structure having three dimensions of 100 nm or less · CPC title
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