Administration of a poly-oxygenated metal hydroxide to reduce the proliferation of carcinoma cells

US9682103B1 · US · B1

Patent metadata
FieldValue
Publication numberUS-9682103-B1
Application numberUS-201615346580-A
CountryUS
Kind codeB1
Filing dateNov 8, 2016
Priority dateMar 30, 2016
Publication dateJun 20, 2017
Grant dateJun 20, 2017

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

A method of treating a condition of a mammal, including a human individual and an animal, by intravenously administering a therapeutically effective amount of a poly -oxygenated metal hydroxide. In some embodiments, the poly-oxygenated metal hydroxide is an aluminum poly-oxygenated hydroxide, such as Ox66™. The poly-oxygenated metal hydroxide may have particles having a diameter of less than or equal to 1 um, and specifically having a diameter of less than or equal to 100 nm. The poly-oxygenated metal hydroxide may be 75-90% colloid or crystalline solution with 10-25% addition of poly-oxygenated metal hydroxide particles.

First claim

Opening claim text (preview).

What is claimed is: 1. A method of treating a human individual, comprising: administering a therapeutically effective amount of a poly-oxygenated aluminum hydroxide composition to a human individual to reduce a proliferation of heptocarcinoma cells (HEPG-2), wherein the poly-oxygenated aluminum hydroxide composition comprises a clathrate containing free oxygen gas (O 2 ) molecules. 2. The method as specified in claim 1 wherein the poly-oxygenated aluminum hydroxide composition is administered intravenously. 3. The method as specified in claim 1 wherein the poly -oxygenated aluminum hydroxide composition comprises poly-oxygenated aluminum hydroxide particles having a diameter of less than or equal to 100 nm. 4. The method as specified in claim 1 wherein the poly -oxygenated aluminum hydroxide composition comprises poly-oxygenated aluminum hydroxide particles having a diameter of less than or equal to 1 um. 5. The method as specified in claim 1 wherein the poly -oxygenated aluminum hydroxide composition is a colloid solution with 10-25% addition of poly-oxygenated aluminum hydroxide. 6. The method as specified in claim 1 wherein the poly -oxygenated aluminum hydroxide composition is a crystalline solution with 10-25% addition of poly-oxygenated aluminum hydroxide. 7. The method as specified in claim 1 wherein the poly -oxygenated aluminum hydroxide composition has a concentration range of 0.1 mg/l to 1000 mg/l. 8. The method as specified in claim 1 wherein the poly -oxygenated aluminum hydroxide composition has poly-oxygenated aluminum hydroxide particles that are surface modified.

Assignees

Inventors

Classifications

  • Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock (artificial tears A61P27/04) · CPC title

  • Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner (non-active ingredients are additionally classified in A61K47/00) · CPC title

  • A61K33/08Primary

    Oxides; Hydroxides · CPC title

  • A61K9/0026Primary

    Blood substitute; Oxygen transporting formulations; Plasma extender · CPC title

  • Nanoparticle, i.e. structure having three dimensions of 100 nm or less · CPC title

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What does patent US9682103B1 cover?
A method of treating a condition of a mammal, including a human individual and an animal, by intravenously administering a therapeutically effective amount of a poly -oxygenated metal hydroxide. In some embodiments, the poly-oxygenated metal hydroxide is an aluminum poly-oxygenated hydroxide, such as Ox66™. The poly-oxygenated metal hydroxide may have particles having a diameter of less than or…
Who is the assignee on this patent?
Univ Baylor
What technology area does this patent fall under?
Primary CPC classification A61K33/08. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Jun 20 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B1). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).