Sugar amides and mixtures thereof
US-2024409523-A1 · Dec 12, 2024 · US
US9675538B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9675538-B2 |
| Application number | US-201314389200-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 27, 2013 |
| Priority date | Mar 30, 2012 |
| Publication date | Jun 13, 2017 |
| Grant date | Jun 13, 2017 |
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An arctigenin derivative used for anti-aging treatment, including protection of the skin from the sun and recovery of skin elasticity. A variety of fatty acid ester derivatives, alcohol ether derivatives and alkylated derivatives are used as the arctigenin derivatives. Agents for controlling ET-1 production, elastase inhibitors, and anti-inflammatory agents are prepared. Such arctigenin derivatives are particularly useful as an external agent for the skin, such as an anti-inflammatory external agent, a sunscreen external agent, or an external agent for recovering elasticity.
Opening claim text (preview).
The invention claimed is: 1. A method for skin whitening in a subject having skin in need of the skin whitening, comprising applying to the skin of the subject an arctigenin derivative represented by the following formula: wherein R represents a C 1 to C 15 alkyl, a C 1 to C 14 alkylcarbonyl, or a hydroxy(C 1 to C 15 )alkyl. 2. The method for skin whitening of claim 1 , wherein said arctigenin derivative is a tyrosinase inhibitor. 3. A method for inhibiting inflammation in a subject in need of inhibition of the inflammation, comprising administering to the subject an arctigenin derivative represented by the following formula: wherein R represents a C 1 to C 15 alkyl, a C 1 to C 14 alkylcarbonyl, or a hydroxy(C 1 to C 15 )alkyl. 4. The method for inhibiting inflammation of claim 3 , wherein said arctigenin derivative is an endothelin-1 production inhibitor.
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