Anti-aging agent containing arctigenin derivative

US9675538B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9675538-B2
Application numberUS-201314389200-A
CountryUS
Kind codeB2
Filing dateMar 27, 2013
Priority dateMar 30, 2012
Publication dateJun 13, 2017
Grant dateJun 13, 2017

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

An arctigenin derivative used for anti-aging treatment, including protection of the skin from the sun and recovery of skin elasticity. A variety of fatty acid ester derivatives, alcohol ether derivatives and alkylated derivatives are used as the arctigenin derivatives. Agents for controlling ET-1 production, elastase inhibitors, and anti-inflammatory agents are prepared. Such arctigenin derivatives are particularly useful as an external agent for the skin, such as an anti-inflammatory external agent, a sunscreen external agent, or an external agent for recovering elasticity.

First claim

Opening claim text (preview).

The invention claimed is: 1. A method for skin whitening in a subject having skin in need of the skin whitening, comprising applying to the skin of the subject an arctigenin derivative represented by the following formula: wherein R represents a C 1 to C 15 alkyl, a C 1 to C 14 alkylcarbonyl, or a hydroxy(C 1 to C 15 )alkyl. 2. The method for skin whitening of claim 1 , wherein said arctigenin derivative is a tyrosinase inhibitor. 3. A method for inhibiting inflammation in a subject in need of inhibition of the inflammation, comprising administering to the subject an arctigenin derivative represented by the following formula: wherein R represents a C 1 to C 15 alkyl, a C 1 to C 14 alkylcarbonyl, or a hydroxy(C 1 to C 15 )alkyl. 4. The method for inhibiting inflammation of claim 3 , wherein said arctigenin derivative is an endothelin-1 production inhibitor.

Assignees

Inventors

Classifications

  • Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title

  • Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] · CPC title

  • Lactones · CPC title

  • Enzyme inhibitors; Enzyme antagonists · CPC title

  • in position 2, the oxygen atom being in its keto or unsubstituted enol form · CPC title

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What does patent US9675538B2 cover?
An arctigenin derivative used for anti-aging treatment, including protection of the skin from the sun and recovery of skin elasticity. A variety of fatty acid ester derivatives, alcohol ether derivatives and alkylated derivatives are used as the arctigenin derivatives. Agents for controlling ET-1 production, elastase inhibitors, and anti-inflammatory agents are prepared. Such arctigenin derivat…
Who is the assignee on this patent?
Rohto Pharma
What technology area does this patent fall under?
Primary CPC classification A61K8/4973. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Jun 13 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).