Estimation of the dry weight of a dialysis patient

Patent metadata

Field	Value
Publication number	US-9675294-B2
Application number	US-201214345856-A
Country	US
Kind code	B2
Filing date	Sep 18, 2012
Priority date	Sep 19, 2011
Publication date	Jun 13, 2017
Grant date	Jun 13, 2017

Abstract

In an embodiment, the invention relates to methods, apparatus, computer programs and computer program products for estimating a dry weight of a dialysis patient comprising the steps of determining a first fluid status of the patient between treatment sessions in a first stage, determining a second fluid status of the patient during treatment sessions in a second stage and estimating the dry weight based on the second fluid status.

First claim

What is claimed is:

1. Method of bringing an initially fluid-overloaded patient into his/her normal fluid status comprising the following steps:
determining at least one interdialytic fluid status of the patient between treatment sessions in a first stage (I);
reducing the fluid overload of the patient based on the interdialytic fluid status;
determining at least one intradialytic fluid status of the patient during treatment sessions in a second stage (II), wherein the intradialytic fluid status is determined based on a continuously monitored evolution of the patient's fluid status during a dialysis session; and
reducing the fluid overload of the patient based on the intradialytic fluid status.

2. Method according to claim 1 , further comprising the following step:
estimating an absolute fluid status difference between a normal fluid status and the interdialytic fluid status, wherein reducing the fluid overload in the first stage (I) is based on the absolute fluid status difference.

3. Method according to claim 2 , further comprising the step of estimating the dry weight of the patient based on the intradialytic fluid status, wherein reducing the fluid overload of the patient in the second stage (II) is based on the estimated dry weight.

4. Method according to claim 3 , further comprising the step(s) of determining an interdialytic fluid status between treatment sessions in a third stage (III) and, optionally, reducing the fluid overload of the patient based on the fluid status in the third stage (III).

5. Method according to claim 4 , wherein the patient's fluid overload is reduced to a level corresponding to a loss of 0.5 kg or less of body weight during a treatment session in the first stage (I), the second stage (II) and/or the third stage (III).

6. Method according to claim 4 , wherein the patient's fluid overload is reduced to a level corresponding to loss of 0.3 kg or less of body weight during a treatment session in the first stage (I), the second stage (II) and/or the third stage (III).

7. Method according to claim 4 , wherein the patient's fluid overload is reduced to a level corresponding to loss of 0.2 kg or less of body weight during a treatment session in the first stage (I), the second stage (II) and/or the third stage (III).

8. Method according to claim 4 , wherein the patient's fluid overload is reduced to a level corresponding to loss of 0.1 kg or less of body weight during a treatment session in the first stage (I), the second stage (II) and/or the third stage (III).

9. A medicament, preferably EPO, antibiotics, and/or other parenterally-administered drugs, to be administered to a patient, wherein the dosage and/or the administration scheme of the medicament is determined based on a dry weight estimated according to the method of claim 1 .

10. Computer readable non-transitory medium with an executable program stored thereon, wherein the program instructs a processing device to execute a method according claim 1 .

11. Computer program product comprising:
a non-transitory machine-readable medium; and
an executable program stored on the non-transitory machine-readable medium, the program being for the execution of a method according claim 1 .

12. Apparatus comprising a memory and a digital signal processor configured to:
determine at least one interdialytic fluid status of the patient between treatment sessions in a first stage (I),
reduce the fluid overload of the patient based on the interdialytic fluid status,
determine at least one intradialytic fluid status of the patient during treatment sessions in a second stage (II), wherein the intradialytic fluid status is determined based on a continuously monitored evolution of the patient's fluid status during a dialysis session, and
reduce the fluid overload of the patient based on the intradialytic fluid status.

Assignees

• Fresenius Medical Care Holdings Inc
• Fresenius Medical Care Deutschland Gmbh

Inventors

• Levin Nathan W
• Zhu Fansan
• Kotanko Peter
• Wabel Peter
• Tetta Ciro

Classifications

• A61B5/4878

  Evaluating oedema · CPC title

• A61B5/0261

  using optical means, e.g. infrared light · CPC title

• A61M2205/3317

  Electromagnetic, inductive or dielectric measuring means · CPC title

• A61B5/0537

  Measuring body composition by impedance, e.g. tissue hydration or fat content · CPC title

• A61M1/1611 Primary

  Weight of the patient · CPC title