Heterocyclic compounds and uses thereof
US-8969363-B2 · Mar 3, 2015 · US
US9670205B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9670205-B2 |
| Application number | US-201615059070-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 2, 2016 |
| Priority date | Mar 4, 2015 |
| Publication date | Jun 6, 2017 |
| Grant date | Jun 6, 2017 |
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The present disclosure relates generally to toll like receptor modulator compounds, such as diamino pyrido[3,2 D]pyrimidine compounds and pharmaceutical compositions which, among other things, modulate toll-like receptors (e.g. TLR-8), and methods of making and using them.
Opening claim text (preview).
We claim: 1. A compound which is or a pharmaceutically acceptable salt thereof. 2. A compound which is 3. A pharmaceutical composition comprising the compound of claim 1 or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient. 4. A pharmaceutical composition comprising the compound of claim 2 , and a pharmaceutically acceptable excipient. 5. A compound which is or a pharmaceutically acceptable salt thereof. 6. A compound which is 7. A pharmaceutical composition comprising the compound of claim 5 or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient. 8. A pharmaceutical composition comprising the compound of claim 6 , and a pharmaceutically acceptable excipient. 9. A compound which is or a pharmaceutically acceptable salt thereof. 10. A compound which is 11. A pharmaceutical composition comprising the compound of claim 9 or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient. 12. A pharmaceutical composition comprising the compound of claim 10 , and a pharmaceutically acceptable excipient. 13. A compound which is or a pharmaceutically acceptable salt thereof. 14. A compound which is 15. A pharmaceutical composition comprising the compound of claim 13 or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient. 16. A pharmaceutical composition comprising the compound of claim 14 , and a pharmaceutically acceptable excipient.
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