Method for producing microparticles by growing a precipitated seed microparticle

Patent metadata

Field	Value
Publication number	US-9669463-B2
Application number	US-201214381848-A
Country	US
Kind code	B2
Filing date	Feb 29, 2012
Priority date	Feb 29, 2012
Publication date	Jun 6, 2017
Grant date	Jun 6, 2017

Abstract

The invention addresses the problem of providing a method for producing microparticles. Provided is a method for producing microparticles. For the first process, seed microparticles are separated in a thin film fluid that forms between at least two processing surfaces, which are disposed facing each other, which can approach or separate from each other and at least one of which rotates relative to the other, and the fluid comprising the separated seed microparticles is discharged as a discharge fluid. Subsequently, for the second process, the separated seed microparticles are grown in the discharged discharge fluid to obtain the intended microparticles. Uniform and homogeneous microparticles are obtained as a result of the microparticle producing method comprising the two process.

First claim

The invention claimed is:

1. A method for producing a microparticle wherein the method comprises at least two steps as following:
(I) a first step of precipitating a seed microparticle in a thin film fluid formed between at least two processing surfaces which are disposed in a position they are faced with each other so as to be able to approach to and separate from each other, at least one of which rotates relative to the other, whereby discharging a fluid which contains the seed microparticle thus precipitated as a discharge fluid, and
(II) a second step of growing the precipitated seed microparticle in the discharge fluid whereby obtaining a prescribed microparticle,
wherein in the second step, into a tubular vessel having an introduction port in one end and a discharge port in other end, the discharge fluid is introduced from the introduction port, whereby growing the seed microparticle in the tubular vessel, and
wherein the first step and the second step are executed continuously.

2. The method for producing a microparticle according to claim 1 wherein the prescribed microparticle is a crystalline microparticle and the seed microparticle is a crystalline microparticle.

3. The method for producing a microparticle according to claim 1 wherein the prescribed microparticle is a crystalline microparticle and the seed microparticle is a crystal nucleus.

4. A method for producing a microparticle wherein
the method is to mix a raw material fluid in which at least one substance to be precipitated is dissolved or molecular dispersed in a solvent with a precipitating fluid to precipitate the substance to be precipitated, whereby precipitating the substance to be precipitated,
the method comprises at least two steps as following:
(I) a first step in which the raw material fluid is mixed with the precipitating fluid in a thin film fluid formed between at least two processing surfaces which are disposed in a position they are faced with each other so as to be able to approach to and separate from each other, at least one of which rotates relative to the other, whereby precipitating a seed microparticle of the substance to be precipitated and discharging a fluid which contains the seed microparticle thus precipitated as a discharge fluid, and
(II) a second step of growing the precipitated seed microparticle in the discharge fluid whereby obtaining a prescribed microparticle,
wherein in the second step, into a tubular vessel having an introduction port in one end and a discharge port in other end, the discharge fluid is introduced from the introduction port, whereby growing the seed microparticle in the tubular vessel, and
wherein the first step and the second step are executed continuously.

5. The method for producing a microparticle according to claim 4 wherein
the raw material fluid is a metal fluid in which at least one metal and/or metal compound is dissolved in a solvent as the substance to be precipitated,
the precipitating fluid is a reducing agent fluid which contains at least one reducing agent, and
the prescribed microparticle is a metal microparticle.

6. The method for producing a microparticle according to claim 1 , wherein a mixer is installed inside the tubular vessel whereby mixing the fluids in the tubular vessel.

7. The method for producing a microparticle according to claim 1 wherein in the second step, the discharge fluid is mixed with a fluid which contains a substance other than the substance of the seed microparticle precipitated, thereby precipitating the other substance on surface of the seed microparticle.

8. The method for producing a microparticle according to claim 1 , wherein a temperature controlling mechanism is installed in the tubular vessel thereby controlling temperature of the fluid in the tubular vessel.

9. The method for producing a microparticle according to claim 1 , wherein by adjusting length and/or diameter of the tubular vessel, a residence time of the fluid in the tubular vessel is controlled.

10. The method for producing a microparticle according to claim 2 wherein in the second step, the discharge fluid is mixed with a fluid which contains a substance other than the substance of the seed microparticle precipitated, thereby precipitating the other substance on surface of the seed microparticle.

11. The method for producing a microparticle according to claim 3 wherein in the second step, the discharge fluid is mixed with a fluid which contains a substance other than the substance of the seed microparticle precipitated, thereby precipitating the other substance on surface of the seed microparticle.

12. The method for producing a microparticle according to claim 4 wherein in the second step, the discharge fluid is mixed with a fluid which contains a substance other than the substance of the seed microparticle precipitated, thereby precipitating the other substance on surface of the seed microparticle.

13. The method for producing a microparticle according to claim 5 wherein in the second step, the discharge fluid is mixed with a fluid which contains a substance other than the substance of the seed microparticle precipitated, thereby precipitating the other substance on surface of the seed microparticle.

14. The method for producing a microparticle according to claim 1 , wherein a space between the at least two processing surfaces is kept at a prescribed distance by a balance between a surface-approaching pressure and a force to separate the at least two processing surfaces from each other.

15. The method for producing a microparticle according to claim 4 , wherein a space between the at least two processing surfaces is kept at a prescribed distance by a balance between a surface-approaching pressure and a force to separate the at least two processing surfaces from each other.

16. The method for producing a microparticle according to claim 1 , wherein in the first step, precipitation of the seed microparticle is performed under a condition of laminar flow in the thin film fluid.

17. The method for producing a microparticle according to claim 4 , wherein in the first step, a raw material fluid and a precipitating fluid are mixed under a condition of laminar flow in the thin film fluid to precipitate the seed microparticle.

18. The method for producing a microparticle according to claim 1 , further comprising:
compared to a case of growing the seed microparticle between the processing surfaces, the seed microparticle being precipitated between the processing surfaces, discharging and obtaining a processing microparticle, shortening a residence time of the fluid containing the seed microparticle between the processing surfaces, thereby increasing a product amount of the prescribed microparticle as well as increasing a flow amount for processing a certain time in a fluid processing apparatus provided with the processing surfaces.

19. The method for producing a microparticle according to claim 4 , further comprising:
compared to a case of growing the seed microparticle between the processing surfaces, the seed microparticle being precipitated between the processing surfaces, discharging and obtaining a processing microparticle, shortening a residence time of the fluid containing the seed microparticle between the processing surfaces, thereby increasing a product amount of the prescribed microparticle as well as increasing a flow amount for processing a certain time in a fluid processing apparatus provided with the processing surfaces.

Assignees

• Enomura Masakazu
• M Technique Co Ltd

Inventors

• Enomura Masakazu

Classifications

• B22F9/24 Primary

  starting from liquid metal compounds, e.g. solutions · CPC title

• B22F9/16 Primary

  using chemical processes · CPC title

• C22B23/04

  by wet processes (recovery or separation of nickel or cobalt using organic agents C22B3/00) · CPC title

• B01F7/00775

  Operations & Transport · mapped topic

• B01J2219/00076

  with heat exchange elements inside the reactor · CPC title