Acyltransferases and uses thereof in fatty acid production
US-9212371-B2 · Dec 15, 2015 · US
US9668960B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9668960-B2 |
| Application number | US-201313797050-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 12, 2013 |
| Priority date | Sep 10, 2008 |
| Publication date | Jun 6, 2017 |
| Grant date | Jun 6, 2017 |
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The invention relates to methods useful in studying or modulating skin or hair pigmentation and to the use of plant extracts in compositions as well as to methods comprising the topical use of such compositions to reduce or to enhance skin or hair pigmentation.
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The invention claimed is: 1. A cosmetic care method comprising applying topically a cosmetic composition comprising at least one plant extract obtainable by a method comprising the steps of: a) providing a test plant extract; b) providing a cell expressing Myosin-X (Myo-X); c) determining the ability of the test plant extract to modulate the expression or the activation of Myo-X in the cell, and d) selecting a plant extract capable to decrease the expression or the activation of Myo-X, as active agent modulating the expression or the activity of Myo-X, to reduce or to enhance skin or hair pigmentation, wherein: said at least one plant extract is selected from the group consisting of an extract of Thalassiosira genus plant, and an Artocarpus heterophyllus seed extract. 2. The cosmetic care method according to claim 1 , wherein the extract of Thalassiosira genus plant is a secretion of Thalassiosira pseudonana. 3. The cosmetic care method according to claim 1 , for the cosmetic treatment of skin or hair depigmentations including those associated with diseases selected from the group consisting of: tinea versicolor, pityriasis alba, lupus erythematosus, mycosis fungoides, sarcoidosis, leprosy, syphilis and nevus depigmentosus. 4. The cosmetic care method according to claim 1 , for the cosmetic treatment of skin or hair hyperpigmentations including those associated with diseases selected from the group consisting of idiopathic melasmas and lentigo. 5. The cosmetic care method according to claim 1 , for the cosmetic treatment of skin surrounding a depigmented area including those associated with vitiligo.
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