Electrolytic eluent recycle device, apparatus and method of use

Patent metadata

Field	Value
Publication number	US-9664655-B2
Application number	US-201314093691-A
Country	US
Kind code	B2
Filing date	Dec 2, 2013
Priority date	Jan 28, 2008
Publication date	May 30, 2017
Grant date	May 30, 2017

Abstract

Electrolytic eluent recycle systems for ion chromatography using a multi-channel electrolytic ion exchange device which integrates suppression, eluent generation, and eluent recycle. The systems recycle the eluent into the analytical system without passing the eluent through the electrode chambers. Also, such systems with a channel for electrolytic removal of ions from the suppression effluent before recycle.

First claim

What is claimed is:

1. A method of using an integrated suppressor and eluent generator apparatus for ion chromatography comprising a suppressor chamber comprising ion exchange material and including an inlet and an outlet, a first electrode chamber comprising a first electrode and including an inlet and an outlet, a second electrode chamber comprising a second electrode and including an inlet and an outlet, an eluent generator chamber comprising flow-through ion exchange material and including an inlet and an outlet, a first barrier preventing significant liquid flow, but permitting transport of ions of only one charge, positive or negative, disposed between said eluent generator chamber and said second electrode chamber, a second barrier preventing significant liquid flow, but permitting transport of ions of only one charge, positive or negative, disposed between said suppressor chamber and said eluent generator chamber, and a third barrier preventing significant liquid flow, but permitting transport of ions of only one charge, positive or negative, disposed between said first electrode chamber and said suppressor chamber, said method comprising
(a) flowing an eluent stream comprising separated ionic species of one charge, positive or negative, through said suppression chamber to suppress said eluent,
(b) recycling said suppressed eluent from said suppressor chamber, directly or indirectly, to said eluent generator chamber,
(c) passing a current between said first and second electrodes through said suppressor chamber and said eluent generator chamber during suppression in step (a) for suppression and eluent generation, and
(d) flowing an aqueous rinse solution through said first and second electrode chambers and between them.

2. The method of claim 1 further comprising
(e) detecting said separated ionic species after step (a) and prior to recycle to said eluent generator chamber.

3. The method of claim 1 further comprising
(e) trapping ions in an ion trap disposed between said suppression chamber and said inlet of said eluent generator chamber.

4. The method of claim 1 further comprising
(e) separating a sample prior to step (a) with a chromatography separator, the chromatography separator including ion exchange material and having an inlet and an outlet, said chromatography separator outlet being in fluid communication with said suppressor chamber inlet.

5. The method of claim 1 , in which said first and second barriers comprise exchangeable ions of opposite charge.

6. The method of claim 5 , in which said third barrier comprises exchangeable ions of a same charge as the second barrier.

7. The method of claim 5 , in which the flow-through ion exchange material is selected from the group consisting of a cation exchange material, an anion exchange material, and a combination thereof.

8. The method of claim 1 , in which the integrated suppressor and eluent generator apparatus further comprises an ion removal chamber, a fourth barrier preventing significant liquid flow, but permitting transport of ions of only one charge, positive or negative, disposed between said ion removal chamber and said suppressor chamber, said method further comprising
(e) flowing said suppressed eluent from said suppressor chamber to said ion removal chamber and then to said eluent generator chamber,
(f) passing said current between said first and second electrodes in step (c) through said suppressor chamber, said ion removal chamber, and said eluent generator chamber, during suppression in step (a) for suppression, removal of ions in said ion removal chamber, and for eluent generation.

9. The method of claim 8 further comprising
(g) detecting said separated ionic species after step (a) and prior to recycle to said eluent generator chamber.

10. The method of claim 8 in which said third and fourth barriers comprise exchangeable barriers of opposite charge.

11. The method of claim 8 in which said second and fourth barriers comprise exchangeable ions of the same charge.

12. The method of claim 8 in which the ion exchange material in said ion removal chamber comprises exchangeable ions selected from the group consisting of a positive charge, a negative charge, and a mixture of positive and negative charges.

13. The method of claim 8 , in which the flow-through ion exchange material is selected from the group consisting of a cation exchange material, an anion exchange material, and a combination thereof.

Assignees

• Dionex Corp

Inventors

• Riviello John M

Classifications

• G01N30/96 Primary

  using ion-exchange (G01N30/02, G01N30/90 take precedence) · CPC title

• G01N2030/965

  suppressor columns · CPC title

• B01D15/36

  involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion · CPC title

• B01D15/16

  relating to the conditioning of the fluid carrier · CPC title