System for forming an array of emulsions
US-9216392-B2 · Dec 22, 2015 · US
DNA analyzer
US9656261B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9656261-B2 |
| Application number | US-201113064094-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 4, 2011 |
| Priority date | Jun 4, 2009 |
| Publication date | May 23, 2017 |
| Grant date | May 23, 2017 |
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- Title
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Abstract
Official abstract text for this publication.
Aspects of the disclosure provide a microfluidic chip to facilitate DNA analysis. The microfluidic chip includes a first domain configured for polymerase chain reaction (PCR) amplification of DNA fragments, a dilution domain coupled to the first domain to dilute a PCR mixture received from the first domain, and a second domain that is coupled to the dilution domain so as to receive the amplified DNA fragments. The second domain includes a separation channel that is configured to perform electrophoretic separation of the amplified DNA fragments. In addition, the disclosure provides a DNA analyzer to act on the microfluidic chip to perform an integrated single chip DNA analysis.
First claim
Opening claim text (preview).
What is claimed is: 1. A microfluidic chip, comprising: an inlet configured to receive a template DNA extracted from a sample acceptor that is external of the microfluidic chip and is fluidically coupled to the microfluidic chip on a cartridge; a first domain configured for polymerase chain reaction (PCR) amplification of DNA fragments, the first domain including a thermal-coupler reservoir coupled with a PCR reservoir for PCR amplification, thermal cycles in the PCR reservoir b…
Assignees
Inventors
Classifications
- B01L7/525Primary
Operations & Transport · mapped topic
Operations & Transport · mapped topic
- B01L3/502753Primary
Operations & Transport · mapped topic
Operations & Transport · mapped topic
Physics · mapped topic
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Frequently asked questions
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- What does patent US9656261B2 cover?
- Aspects of the disclosure provide a microfluidic chip to facilitate DNA analysis. The microfluidic chip includes a first domain configured for polymerase chain reaction (PCR) amplification of DNA fragments, a dilution domain coupled to the first domain to dilute a PCR mixture received from the first domain, and a second domain that is coupled to the dilution domain so as to receive the amplifie…
- Who is the assignee on this patent?
- Bell H Randall, Bienvenue Joan M, Pettit John W, and 8 more
- What technology area does this patent fall under?
- Primary CPC classification B01L7/525. Mapped technology areas include Operations & Transport.
- When was this patent published?
- Publication date Tue May 23 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).