Light protecting-effective cosmetic or dermatological preparations

Patent metadata

Field	Value
Publication number	US-9656103-B2
Application number	US-63268605-A
Country	US
Kind code	B2
Filing date	Jul 11, 2005
Priority date	Jul 20, 2004
Publication date	May 23, 2017
Grant date	May 23, 2017

Abstract

Disclosed is the use of an insoluble or sparingly soluble micronized substance class which is not a cosmetic UV absorber and which is dispersed in the oil- or water-phase of a cosmetic or dermatological composition for the enhancement of light protecting action of this cosmetic or dermatological composition comprising at least one cosmetic UV filter which is soluble in the water- or oil-phase. The cosmetic preparation according to the invention shows a remarkable increase in SPF.

First claim

The invention claimed is:

1. A method for the enhancement of light protection of a cosmetic or dermatological composition, said method comprising
dispersing insoluble or sparingly soluble micronized birefringent particles having an average refractive index of n=1 to 2.5 and a Δn=0.001 to 0.8 in an oil or water phase of a cosmetic or dermatological composition and the birefringent particles are selected from the group consisting of melamine polyphosphate, melamine cyanurate, melamine phosphate, melam (1,3,5-triazine-2,4,6-triamine-n-(4,6-diamino-1,3,5-triazine-2-yl) of the formula

melem (-2,5,8-triamino 1,3,4,6,7,9,9b-heptaazaphenalene) of the formula

melon (poly [8-amino-1,3,4,6,7,9,9b-heptaazaphenalene-2,5-diyl]imino) of the formula

1,3,5-triazin-2(1H)-one, 4,6-diamino of the formula

1,3,5-triazine-2,4(1H,3H)-dione, 6-amino- of the formula

benzene-1,2,4,5-tetracarboxamide, biphenyl-4,4′-dicarboxamide, biphenyl-4-carboxylic amide,
isophthalamide and terephthalamide;
cyanuric acid, diphenyl urea, propylurea, 3-methyl-1,1-diphenylurea;
Isatin; 5-amino-isophthalic acid; diphenyl sulfone, and
a triazine compound of the formula

wherein the insoluble or sparingly soluble micronized birefringent particles have a particle size from 0.02 to 10 micrometers, and
wherein said composition further comprises at least one cosmetic UV filter that is soluble in the water or oil phase.

2. A method according to claim 1 , wherein the birefringent particles contain a hydrophobic or hydrophilic surface.

3. A method according to claim 1 , wherein the birefringent particles are crystalline or semi-crystalline.

4. A method according to claim 1 , wherein the birefringent particles are a high melting solid, wherein the high melting solid has a melting point of >80° C.

5. A method according to claim 1 , wherein the oil phase comprises a UV filter selected from the group consisting of p-aminobenzoic acid derivatives, salicylic acid derivatives, benzophenone derivatives, dibenzoylmethane derivatives, diphenyl acrylate derivatives, benzofuran derivatives, polymeric UV absorbers comprising one or more organosilicon radicals, cinnamic acid derivatives, camphor derivatives, trianilino-s-triazine derivatives, s-triazine derivatives, phenylbenzimidazolesulfonic acid and salts thereof, menthyl anthranilates and benzotriazole derivatives.

6. A method according to claim 5 , wherein the UV filter is selected from the group consisting of
(+/−)-1,7,7-trimethyl-3-[(4-methylpheny)methylenelbicyclo[2.2.1]heptan-2-one; 1,7,7-trimethyl-3-(phenylmethylene)bicyclo[2.2.1]heptan-2-one; (2-hydroxy-4-methoxyphenyl)(4-methylphenyl)methanone; 2,4-dihydroxybenzophenone; 2,2′,4,4′-tetrahydroxybenzophenone; 2-hydroxy-4-methoxy benzophenone; 2,2′-dihydroxy-4,4′-dimethoxybenzophenone; 2,2′-dihydroxy-4-methoxybenzophenone; 1-[4-(1,1-dimethylethyl)phenyl]-3-(4-methoxyphenyl)propane-1,3-dione; 3,3,5-trimethyl cyclohexyl-2-hydroxy benzoate; isopentyl p-methoxycinnamate; menthyl-o-aminobenzoate; menthyl salicylates; 2-ethylhexyl 2-cyano,3,3-diphenylacrylate; 2- ethylhexyl 4-(dimethylamino)benzoate; 2- ethylhexyl 4- methoxycinnamate; 2- ethylhexyl salicylates; benzoic acid, 4,4′,4″-(1,3,5-triazine-2,4,6-triyltriimino)tris-, tris(2-ethylhexyl)ester; 2,4,6-trianilino-(p-carbo-2′-ethylhexyl-1′-oxi)-1,3,5-triazine; benzoic acid, 4-amino-, ethyl ester, polymer with oxirane; 2-propenamide, N-[[4-[(4,7,7-trimethyl-3-oxobicyclo[2.2.1]hept-2-ylidene)methyllphenyllmethyll-, homopolymers; triethanolamine salicylates; 2,2′-methylene-bis-[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)-phenol]; 2,4-bis{[4-(2-ethylhexyloxy)-2-hydroxyl-phenyll-6-(4-methoxyphenyl)-(1,3,5)-triazine; benzoic acid, 4,4′-[[6-[[4-[[(1,1-dimethylethyl)aminolcarbonyllphenyllamino]1,3,5-triazine-2,4-diylldiiminolbis-, bis(2-ethylhexyl)ester; phenol, 2-(2H-benzotriazol-2-yl)-4-methyl -6-[2-methyl-3-[1,3,3,3-tetramethyl-1-[(trimethylsilyl)oxyldisiloxanyllpropyll-; dimethicodiethylbezalmalonate; benzoic acid, 2-[4-(diethylamino)-2-hydroxybenzoyll-, hexyl ester; 1,3,5-triazine, 2,4,6-tris(4-methoxyphenyl)-; 1,3,5-triazine, 2,4,6-tris[4-[(2-ethylhexyl)oxylphenyl]-; 2-propenoic acid, 3-(1 H-imidazol-4-yl)-; benzoic acid, 2-hydroxy-, [4-(1-methylethyl)phenyllmethyl ester; 1,2,3-propanetriol, 1-(4-aminobenzoate); benzeneacetic acid, 3,4-dimethoxy-a-oxo-; 2-propenoic acid, 2-cyano-3,3-diphenyl-, ethyl ester; anthralinic acid, p-menth-3-yl ester; and 1,3,5-triazine-2,4,6-triamine, N,N′-bis[4-[5-(1,1-dimethylpropyl)-2-benzoxazolyl]phenyll-N″-(2-ethylhexyl)-.

7. A method according to claim 1 , wherein the water-phase comprises at least one UV filter selected from the group consisting of
2-hydroxy-4-methoxy benzophenone-5-sulfonic acid; alpha-(2-oxoborn-3-ylidene)toluene-4-sulphonic acid and its salts; methyl N,N,N-trimethyl-4-[(4,7,7-trimethyl-3-oxobicyclo[2,2,1]hept-2-ylidene)methyllanilinium sulphate; 4-aminobenzoic acid; 2-phenyl-1H-benzimidazole-5-sulphonic acid; 3,3′-(1,4-phenylenedimethylene)bis[7,7-dimethyl-2-oxo-bicyclo[2.2.1]heptane-1-methanesulfonic acid]; 1H-benzimidazole-4,6-disulfonic acid, 2,2′-(1,4-phenylene)bis-, disodium salt; benzenesulfonic acid, 3-(2H-benzotriazol-2-yl)-4-hydroxy-5-(1-methylpropyl)-, monosodium salt; 1-dodecanaminium, N-[3-[[4-(dimethylamino)benzoyllaminolpropyl]N,N-dimethyl-, salt with 4-methylbenzenesulfonic acid (1:1); 1-propanaminium, N,N,N-trimethyl-3-[(1-oxo-3-phenyl-2-propenyl)aminol-, chloride; 1 H-benzimidazole-4,6-disulfonic acid, 2,2′-(1,4-phenylene)bis-; 1-propanaminium, 3-[[3-[3-(2H-benzotriazol-2-yl)-5-(1,1-dimethylethyl)-4-hydroxyphenyll-1-oxopropyllaminol-N,N-diethyl-N-methyl-, methyl sulfate (salt); and 2,2′-bis(1,4-phenylene)-1H-benzimidazole-4,6-disulphonic acid mono sodium salt and disodium phenyl dibenzimidazole tetrasulfonate.

8. A cosmetic or dermatological composition comprising:
(a) a water phase,
(b) an oil phase,
(c) a UV-Filter which can be formulated in the oil phase or in the water phase,
(d) insoluble or sparingly soluble micronized birefringent particles having an average refractive index of n=1 to 2.5 and a Δn=0.001 to 0.8 selected from the group consisting of melamine polyphosphate, melamine cyanurate, melamine phosphate, melam (1,3,5-triazine-2,4,6-triamine-n-(4,6-diamino-1,3,5-triazine-2-yl) of the formula

melem (-2,5,8-triamino 1,3,4,6,7,9,9b-heptaazaphenalene) of the formula

melon (poly[8-amino-1,3,4,6,7,9,9b-heptaazaphenalene-2,5-diyl]imino) of the formula

1,3,5-triazin-2(1H)-one, 4,6-diamino of the formula

1,3,5-triazine-2,4(1H,3H)-dione, 6-amino- of the formula

Assignees

• Müller Stefan
• Ehlis Thomas
• Giesinger Jochen
• Kreyer Gilbert
• Basf Se

Inventors

• Müller Stefan
• Ehlis Thomas
• Giesinger Jochen
• Kreyer Gilbert

Classifications

• A61Q17/04 Primary

  Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations · CPC title

• A61K9/107 Primary

  Emulsions {; Emulsion preconcentrates; Micelles (composition of emulsions A61K47/00)} · CPC title

• A61K8/02 Primary

  characterised by special physical form · CPC title

• A61K2800/412

  Microsized, i.e. having sizes between 0.1 and 100 microns · CPC title

• A61K8/49 Primary

  containing heterocyclic compounds · CPC title