Polymer based hydrogel

Patent metadata

Field	Value
Publication number	US-9655990-B2
Application number	US-201414783081-A
Country	US
Kind code	B2
Filing date	Apr 8, 2014
Priority date	Apr 8, 2013
Publication date	May 23, 2017
Grant date	May 23, 2017

Abstract

The present invention relates to an anti-aging antimicrobial wound healing polymer based hydrogel. In the study of the present invention, a wound healing gel formulation is developed by combining poloxamer polymers and boron component at adequate concentrations in a carbopol based gel. The said gel exhibits fast action on the damaged area and prevents scar formation.

First claim

The invention claimed is:

1. An anti-aging, wound-healing and antimicrobial hydrogel, which is comprising: 3% boron compound, 4% poloxamer and 1% gel; wherein the boron compound and the poloxamer are added to the gel that is prepared as a carrier, wherein the boron compound is selected from a group consisting of sodium pentaborate pentahydrate, boric acid, alkaline and alkaline earth metal borates and all hydrate forms of these borates, ammonium borates, and boric acid esters.

2. The hydrogel according to claim 1 , wherein the gel comprises carbopol.

3. The hydrogel according to claim 1 , wherein the boron derivative is a sodium pentaborate pentahydrate.

4. The hydrogel according to claim 1 , wherein a mixture of the gel, the boron compound and the poloxamer are stored at 4° C. for 16-24 hours before it can be used.

5. The hydrogel according to claim 1 , wherein the boron compound is a boric acid.

6. The hydrogel according to claim 1 , wherein the boron compound is alkaline metal borates.

7. The hydrogel according to claim 1 , wherein the boron compound is alkaline earth metal borates.

8. The hydrogel according to claim 1 , wherein the form of the hydrogel is selected from a group consisting of lotion, cream, emulsion, spray, foam, gelatin, paste, powder, plaster, skin plate, and wound dressing textile product.

Assignees

• Univ Yeditepe

Inventors

• Sahin Fikrettin
• Demirci Selami
• Dogan Aysegul

Classifications

• A61P31/00

  Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics · CPC title

• A61P43/00

  Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title

• A61P17/02

  for treating wounds, ulcers, burns, scars, keloids, or the like · CPC title

• A61P17/00

  Drugs for dermatological disorders · CPC title

• A61Q19/08

  Anti-ageing preparations · CPC title