Sporicidal formulation including amine oxide surfactant and a mixture of oxidants

Patent metadata

Field	Value
Publication number	US-9648875-B2
Application number	US-201114347446-A
Country	US
Kind code	B2
Filing date	Oct 28, 2011
Priority date	Oct 28, 2011
Publication date	May 16, 2017
Grant date	May 16, 2017

Abstract

Formulations and wipes for imparting a sporicide to a surface are disclosed herein. To achieve the sporicidal efficacy of the product, a synergistic amount of an amine oxide surfactant and a mixture of oxidants is incorporated into the formulation. The operative sporicidal formulation contains a solvent, an amine oxide surfactant, a water soluble oxidant and a water insoluble oxidant. Typically, the formulation can contain about 0.05 to about 3.7 percent (by weight of the formulation) of an amine oxide surfactant, about 0.5 to about 4 percent (by weight of the formulation) of a water soluble oxidant, and about 0.1 to about 6 percent (by weight of the formulation) of a water insoluble oxidant.

First claim

The invention claimed is:

1. A sporicidal formulation comprising:
a solvent;
about 0.05 to about 3.7 percent (by weight of the formulation) of an amine oxide surfactant, wherein the amine oxide surfactant is lauramine oxide;
about 0.5 to about 4 percent (by weight of the formulation) of a water soluble oxidant, wherein the water soluble oxidant is hydrogen peroxide; and
about 0.1 to about 6 percent (by weight of the formulation) of a water insoluble oxidant, wherein the water insoluble oxidant is benzoyl peroxide.

2. The sporicidal formulation of claim 1 wherein the formulation comprises from about 0.1 to about 2.5 percent (by weight of the formulation) of the amine oxide surfactant.

3. The sporicidal formulation of claim 1 further comprising an organic acid wherein the organic acid is selected from the group consisting of benzoic acid, malic acid, lactic acid, citric acid, propionic acid, acetic acid, and combinations thereof.

4. The sporicidal formulation of claim 1 wherein the solvent is selected from the group consisting of ethanol, dimethyl isosorbide, isopropanol, ethoxydiglycol, water, acetone, and combinations thereof.

5. The sporicidal formulation of claim 1 further comprising a peroxide stabilizer wherein the peroxide stabilizer is selected from the group consisting of etidronic acid, sodium pyrophosphate, sodium hexametaphosphate, pentasodium diethylenetriaminepentaacetate, ethylenediaminetetraacetic acid, allymethyacrylates copolymer, and combinations thereof.

6. A wipe comprising:
a wipe substrate; and
a sporicidal formulation comprising:
a solvent;
about 0.05 to about 3.7 percent (by weight of the formulation) of an amine oxide surfactant, wherein the amine oxide surfactant is lauramine oxide;
about 0.5 to about 4 percent (by weight of the formulation) of a water soluble oxidant, wherein the water soluble oxidant is hydrogen peroxide; and
about 0.1 to about 6 percent (by weight of the formulation) of a water insoluble oxidant, wherein the water insoluble oxidant is benzoyl peroxide.

7. The wipe of claim 6 wherein the composition comprises from about 0.1 to about 2.5 percent (by weight of the formulation) of the amine oxide surfactant.

8. The wipe of claim 6 further comprising an organic acid wherein the organic acid is selected from the group consisting of benzoic acid, malic acid, lactic acid, citric acid, propionic acid, acetic acid, and combinations thereof.

9. The wipe of claim 6 wherein the solvent is selected from the group consisting of ethanol, dimethyl isosorbide, isopropanol, ethoxydiglycol, water, acetone, and combinations thereof.

10. The wipe of claim 6 further comprising a peroxide stabilizer wherein the peroxide stabilizer is selected from the group consisting of etidronic acid, sodium pyrophosphate, sodium hexametaphosphate, pentasodium diethylenetriaminepentaacetate, allymethyacrylates copolymer, and combinations thereof.

Assignees

• Koenig David William
• Hoffman Douglas Robert
• Huang Yang
• He Aimin
• Kimberly Clark Co

Inventors

• Koenig David William
• Hoffman Douglas Robert
• Huang Yang
• He Aimin

Classifications

• A61Q17/005

  Antimicrobial preparations · CPC title

• A01N33/24 Primary

  only one oxygen atom attached to the nitrogen atom · CPC title

• A47K2010/3266

  Wet wipes · CPC title

• A61K9/7007

  Drug-containing films, membranes or sheets (A61K9/0041, A61K9/0043, A61K9/006, A61K9/0063 take precedence) · CPC title

• A61K8/0208

  Tissues; Wipes; Patches · CPC title