Method for setting a blood transfusion parameter

Patent metadata

Field	Value
Publication number	US-9646375-B2
Application number	US-201314072632-A
Country	US
Kind code	B2
Filing date	Nov 5, 2013
Priority date	Jul 9, 2011
Publication date	May 9, 2017
Grant date	May 9, 2017

Abstract

One variation of a method for setting a blood transfusion parameter for a patient includes identifying a blood transfusion bag in a photographic image; extracting a color feature from a region of the photographic image corresponding to the blood transfusion bag; estimating a blood component content within the blood transfusion bag based on the color feature; and triggering transfusion from the blood transfusion bag based on the blood component content within the blood transfusion bag and an estimated volemic status of the patient.

First claim

We claim:

1. A method for setting a blood transfusion parameter for a patient, the method comprising:
identifying, at a computing system, a blood transfusion bag in a photographic image generated using an optical sensor in communication with the computing system, and, in a region of the photographic image, a fluid surface within the blood transfusion bag;
extracting, at the computing system, a color feature from a region of the photographic image corresponding to the blood transfusion bag;
identifying, at the computing system, a volume marker printed on the blood transfusion bag in the region of the photographic image;
generating, at the computing system, an estimated volume of fluid in the blood transfusion bag based on the volume marker and the fluid surface;
estimating, at the computing system, a blood component content within the blood transfusion bag based on the color feature and the estimated volume of fluid; and
triggering transfusion from the blood transfusion bag based on the blood component content within the blood transfusion bag and an estimated volemic status of the patient.

2. The method of claim 1 , wherein extracting the color feature from the region of the photographic image comprises extracting the color value in the red component space from the region of the photographic image, and wherein estimating the blood component content within the blood transfusion bag comprises estimating a concentration of red blood cells in the blood transfusion bag based on the redness value of the region of the photographic image.

3. The method of claim 2 , wherein extracting the color feature from the region of the photographic image further comprises extracting a second color value in the blue component space and a third color value in the green component space from the region of the photographic image, and wherein estimating the blood component content within the blood transfusion bag further comprises estimating a concentration of free hemoglobin in the blood transfusion bag based on the color value, the second color value, and the third color value.

4. The method of claim 2 , wherein identifying the blood transfusion bag in the photographic image comprises implementing optical character recognition to identify text printed on the blood transfusion bag and further comprising determining a volume of fluid in the blood transfusion bag based on identified text printed on the blood transfusion bag, estimating a red blood cell mass in the blood transfusion bag based on the concentration of red blood cells and the volume of fluid in the blood transfusion bag, and calculating a blood transfusion stop time based on the red blood cell mass in the blood transfusion bag and the volemic status of the patient.

5. The method of claim 1 , further comprising
receiving a second image of a physical substrate,
extracting a feature from a region of the second image corresponding to the physical substrate,
estimating the blood component content in the physical substrate based on the extracted feature,
updating a blood loss history of the patient with the blood component content based on a timestamp of the second image,
predicting a current hematocrit of the patient based on the blood loss history of the patient, and
estimating the volemic status of the patient, the volemic status of the patient defining a difference between the current hematocrit of the patient and a target hematocrit of the patient.

6. The method of claim 5 , wherein extracting the feature from the region of the second image comprises extracting the feature from the region of the second image corresponding to one of a suction canister, a gauze sponge, a surgical towel, and a surgical drape.

7. The method of claim 5 , further comprising estimating an intracirculatory blood volume of the patient based on the blood loss history and an infusion history of the patient, wherein triggering transfusion from the blood transfusion bag comprises predicting achievement of the target hematocrit of the patient based on the intracirculatory blood volume of the patient, the current hematocrit of the patient, and the blood component content within the blood transfusion bag.

8. The method of claim 1 , further comprising estimating a preferred transfusion rate from the blood transfusion bag to achieve a target hematocrit of the patient, based on the estimated volemic status and the blood component content within the blood transfusion bag.

9. The method of claim 5 , further comprising extrapolating a volemic status trend of the patient from the blood loss history of the patient, wherein calculating the transfusion rate from the blood transfusion bag comprises calculating the transfusion rate from the blood transfusion bag to offset a predicted future volemic status of the patient based on the volemic status trend of the patient.

10. The method of claim 8 , further comprising updating the transfusion rate over time based on the volemic status trend and an estimated blood component content in a second physical substrate.

11. The method of claim 1 , wherein identifying the blood transfusion bag in the photographic image comprises identifying an autologous blood transfusion bag in the photographic image.

12. The method of claim 1 , wherein identifying the blood transfusion bag in the photographic image comprises extracting a barcode from the region of the photographic image corresponding to the blood transfusion bag and retrieving, from a database, a set of data pertaining to allogeneic blood contained in the blood transfusion bag based on the extracted barcode.

13. The method of claim 12 , further comprising capturing the photographic image with a camera integrated into a mobile computing device, receiving a Global Positioning System location from a corresponding sensor in the mobile computing device, and transmitting delivery confirmation for the blood transfusion bag to the database in response to the Global Positioning System location with a threshold range of a target location specified in the set of data pertaining to the blood transfusion bag.

14. The method of claim 13 , wherein triggering transfusion from the blood transfusion bag comprises displaying an alarm to initiate transfusion from the blood transfusion bag on a display integrated into the mobile computing device.

15. The method of claim 1 , wherein identifying the blood transfusion bag in the photographic image comprises implementing edge detection to identify the region of the photographic image corresponding to the blood transfusion bag and estimating a volume of fluid in the blood transfusion bag based on a perimeter shape of the region.

16. A method for setting a blood transfusion parameter for a patient, the method comprising:
identifying, at a computing system, a blood transfusion bag in a photographic image generated using an optical sensor in communication with the computing system, comprising extracting a barcode, from a region of the photographic image corresponding to the blood transfusion bag and retrieving, from a database, a set of data pertaining to allogeneic blood contained in the blood transfusion bag based on the extracted barcode;
extracting, at the computing system, a color feature from a region of the photographic image corresponding to the blood transfusion bag;
identifying, at the computing system, a volume marker printed on the blood transfusion bag in the region of the photographic image;
estimating, at the computing system, a blood component content within the blood transfusion bag based on the color feature; and
triggering transfusion from the blood transfusion bag based

Assignees

• Gauss Surgical Inc

Inventors

• Satish Siddarth
• Miller Kevin
• Zandifar Ali

Classifications

• A61M1/024

  Means for controlling the quantity of transfused blood, e.g. by weighing the container and automatic stopping of the transfusion after reaching a determined amount · CPC title

• A61M2205/3379

  Masses, volumes, levels of fluids in reservoirs, flow rates · CPC title

• G06T2207/30024

  Cell structures in vitro; Tissue sections in vitro · CPC title

• G06T2207/10024

  Color image · CPC title

• G06T7/0012 Primary

  Biomedical image inspection · CPC title