Microbiome identification and bacteriophage formulations
US-2024123002-A1 · Apr 18, 2024 · US
Immunoreactive protein orthologs of Ehrlichia canis and E. chaffeensis
US9645148B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9645148-B2 |
| Application number | US-201514818221-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 4, 2015 |
| Priority date | Jun 16, 2005 |
| Publication date | May 9, 2017 |
| Grant date | May 9, 2017 |
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- Title
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Abstract
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The present invention concerns gp36 immunoreactive compositions for E. canis and gp 47 immunoreactive compositions for E. chaffeensis . In particular, epitopes for E. canis gp36 and E. chaffeensis gp 47 are disclosed. In certain embodiments, the immunoreactive compositions comprise tandem repeats having carbohydrate moieties.
First claim
Opening claim text (preview).
What is claimed is: 1. A method of identifying an E. canis or E. chaffeensis infection using a sample from an individual suspected of having such an infection, comprising assaying the sample for an antibody that immunologically binds a polypeptide consisting of: (a) a sequence selected from the group consisting of SEQ ID NO:45 and SEQ ID NO:22; or (b) a sequence selected from the group consisting of SEQ ID NO:25, SEQ ID NO:26, SEQ ID NO:27, SEQ ID NO:28, SEQ ID NO:23 and SEQ ID NO:24 wherein the sample is assayed by means of an immunoassay in which antibodies from the sample, if present, will bind to an immobilized polypeptide comprising a sequence at least 90% identical to the sequence of (a) or (b), and further wherein bound antibodies are detected by means of a detectable label. 2. The method of claim 1 , wherein the immunoassay is a enzyme linked immunosorbent assay (ELISA), radioimmunoassay (RIA), immunoradiometric assay, fluoroimmunoassay, chemiluminescent assay, bioluminescent assay, or a Western blot. 3. The method of claim 1 , wherein the sample is assayed by contacting an immobilized polypeptide comprising a sequence selected from the group consisting of SEQ ID NO:45 and SEQ ID NO:22, with said sample and detecting immunological binding of the antibody thereto. 4. The method of claim 1 , wherein the sample is assayed by contacting an immobilized polypeptide comprising SEQ ID NO: 22, with said sample and detecting immunological binding of the antibody thereto. 5. The method of claim 1 , wherein the sample is assayed by contacting an immobilized polypeptide comprising a sequence selected from the group consisting of SEQ ID NO:25, SEQ ID NO:26, SEQ ID NO:27, SEQ ID NO:28, SEQ ID NO:23 and SEQ ID NO:24, with said sample and detecting immunological binding of the antibody thereto. 6. The method of claim 1 , wherein the sample is assayed by contacting an immobilized polypeptide comprising SEQ ID NO:23 or SEQ ID NO:24, with said sample and detecting immunological binding of the antibody thereto. 7. The method of claim 1 , wherein the immobilized polypeptide comprises SEQ ID NO:45. 8. The method of claim 1 , wherein the immobilized polypeptide comprises SEQ ID NO:25. 9. The method of claim 1 , wherein the immobilized polypeptide comprises SEQ ID NO:26. 10. The method of claim 1 , wherein the immobilized polypeptide comprises SEQ ID NO:27. 11. The method of claim 1 , wherein the immobilized polypeptide comprises SEQ ID NO:28. 12. The method of claim 1 , wherein the immobilized polypeptide comprises SEQ ID NO:23. 13. The method of claim 1 , wherein the immobilized polypeptide comprises SEQ ID NO:24.
Assignees
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Classifications
from Richettsiales (O) · CPC title
- G01N33/56911Primary
Bacteria · CPC title
Detection of antigens from microorganism in sample from host · CPC title
from bacteria · CPC title
- C07K16/1246Primary
Rickettsiales (O) · CPC title
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Frequently asked questions
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- What does patent US9645148B2 cover?
- The present invention concerns gp36 immunoreactive compositions for E. canis and gp 47 immunoreactive compositions for E. chaffeensis . In particular, epitopes for E. canis gp36 and E. chaffeensis gp 47 are disclosed. In certain embodiments, the immunoreactive compositions comprise tandem repeats having carbohydrate moieties.
- Who is the assignee on this patent?
- Res Dev Foundation
- What technology area does this patent fall under?
- Primary CPC classification G01N33/56911. Mapped technology areas include Physics.
- When was this patent published?
- Publication date Tue May 09 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).