Mitigating necrosis in transgenic glyphosate-tolerant cotton plants treated with herbicidal glyphosate formulations

Patent metadata

Field	Value
Publication number	US-9642359-B2
Application number	US-201615155290-A
Country	US
Kind code	B2
Filing date	May 16, 2016
Priority date	Mar 4, 2005
Publication date	May 9, 2017
Grant date	May 9, 2017

Abstract

This invention relates generally to improved methods and herbicidal glyphosate compositions for use in controlling the growth of weeds and unwanted vegetation, and particularly for use in controlling weeds in a crop of transgenic glyphosate-tolerant cotton plants by over-the-top, foliar application of a herbicidal glyphosate formulation.

First claim

What is claimed is:

1. A method of safening an herbicidal glyphosate composition against the occurrence of N-(phosphonomethyl)iminodiacetic acid-induced leaf necrosis in transgenic glyphosate-tolerant cotton plants,
the method comprising combining an herbicidal glyphosate composition with an additive composition and water, wherein
the herbicidal glyphosate composition comprises N-(phosphonomethyl)glycine in the form of an agronomically acceptable salt thereof, and N-(phosphonomethyl)iminodiacetic acid or a salt thereof; and
the additive composition comprises a safening agent comprising a metal ion selected from the group consisting of aluminum, antimony, iron, chromium, nickel, manganese, cobalt, copper, zinc, vanadium, titanium, molybdenum, tin, barium and mixtures thereof;
thereby producing a safened aqueous herbicidal glyphosate spray composition wherein the molar ratio of metal ions to N-(phosphonomethyl)iminodiacetic acid equivalent is at least about 0.15:1.

2. The method of claim 1 wherein the additive composition is in the form of a liquid composition, and wherein the additive composition further comprises a solubilizing ligand that assists in maintaining the metal ion in solution such that the metal ion is available to form a complex or salt with N-(phosphonomethyl)iminodiacetic acid or an anion formed by deprotonation or partial deprotonation thereof.

3. The method of claim 2 wherein the solubilizing ligand is selected from the group consisting of polyacids, hydroxyl acids, an anhydride, ester, amide, halide salt or precursor thereof, polyhydroxy compounds, amino acids, proteins, polysaccharides and mixtures thereof.

4. The method of claim 3 wherein the solubilizing ligand comprises a polycarboxylic acid.

5. The method of claim 4 wherein the solubilizing ligand comprises citric acid.

6. The method of claim 2 wherein the solubilizing ligand is present in the additive composition in molar excess relative to the metal ion.

7. The method of claim 6 wherein the molar ratio of solubilizing ligand to metal ion is from about 1.5:1 to about 4:1.

8. The method of claim 1 wherein the safening agent comprises a metal ion that is subject to formation of a complex or salt with N-(phosphonomethyl)iminodiacetic acid or an anion formed by deprotonation or partial deprotonation thereof, the formation of such complex or salt being effective to inhibit significant leaf necrosis in the crop of transgenic glyphosate-tolerant cotton plants induced by N-(phosphonomethyl)iminodiacetic acid or salt thereof present in the composition.

9. The method of claim 1 wherein the metal ion is polyvalent.

10. The method of claim 9 wherein the metal ion is selected from the group consisting of aluminum, copper, iron, zinc and mixtures thereof.

11. The method of claim 10 wherein the safening agent comprises a mixture of iron and zinc metal ions or a mixture of iron and copper metal ions.

12. The method of claim 10 wherein the metal ion safening agent comprises polyvalent iron ions.

13. The method of claim 12 wherein the metal ion safening agent is derived from a compound selected from the group consisting of ferric sulfate, ferric chloride, iron salts of di-, tri- and other polycarboxylic acids and mixtures thereof.

14. The method of claim 13 wherein the molar ratio of metal ions to N-(phosphonomethyl)iminodiacetic acid equivalent in the safened herbicidal glyphosate spray composition is at least about 0.4:1.

15. The method of claim 14 wherein the molar ratio of metal ions to N-(phosphonomethyl)iminodiacetic acid equivalent in the safened herbicidal glyphosate spray composition is no greater than about 25:1.

16. The method of claim 14 wherein the molar ratio of metal ions to N-(phosphonomethyl)iminodiacetic acid equivalent in the safened herbicidal glyphosate spray composition is from about 0.5:1 to about 25:1.

17. The method of claim 1 wherein the herbicidal glyphosate composition comprises N-(phosphonomethyl)glycine in the form of an alkali metal salt, an ammonium salt, a diammonium salt, an alkylamine salt, an alkanolamine salt, an alkylsulfonium salt, a sulfoxonium salt, or a mixture or combination thereof.

18. The method of claim 17 wherein the N-(phosphonomethyl)glycine is predominantly present in the form of a salt thereof selected from the group consisting of sodium salt, potassium salt, isopropylamine salt, ethanolamine salt, trimethylsulfonium salt, and mixtures or combinations thereof.

19. The method of claim 18 wherein the N-(phosphonomethyl)glycine is predominantly present in the form of the isopropylamine salt.

20. The method of claim 18 wherein the N-(phosphonomethyl)glycine is predominantly present in the form of the potassium salt.

21. The method of claim 1 wherein the herbicidal glyphosate composition further comprises a surfactant component.

22. The method of claim 21 wherein the surfactant component comprises a cationic surfactant selected from the group comprising alkylamines, alkyletheramines, alkylamine alkoxylates, alkyletheramine alkoxylates, quaternary alkylamines, quaternary alkyletheramines, alkoxylated quaternary alkylamines, alkoxylated quaternary alkyletheramines, alkylamine acetates, amine oxides, alkoxylated amine oxides, alkoxylated etheramine oxides, and salts and mixtures thereof.

23. The method of claim 22 wherein the herbicidal glyphosate composition further comprises an alkylglucoside surfactant wherein the alkyl has from 4 to 18 carbon atoms and the surfactant contains from 1 to 3 glucoside units per alkyl unit.

24. The method of claim 21 wherein the glyphosate is predominantly in the form of the potassium salt of N-(phosphonomethyl)glycine and the herbicidal glyphosate composition further comprises a surfactant component comprising an ethoxylated alkylamine surfactant of formula (3)

wherein m+n is between about 2 and about 25 and R is a branched or straight chain alkyl group having from about 12 to about 22 carbon atoms.

25. The method of claim 21 wherein glyphosate is predominantly in the form of the potassium salt of N-(phosphonomethyl)glycine and the herbicidal glyphosate composition further comprises a surfactant component comprising a surfactant of formula (4)

wherein R 1 is a straight or branched chain C 6 to about C 22 alkyl, aryl or alkylaryl group, m is an average number from 1 to about 10, R 2 in each of the m (O—R 2 ) groups is independently C 1 -C 4 alkylene, R 3 groups are independently C 1 -C 4 alkylene, and x and y are average numbers such that x+y is in the range from 2 to about 60.

Assignees

• Monsanto Technology Llc

Inventors

• Prosch Stephen D
• Seitz Michael E
• Eaton David R
• Becher David Z

Classifications

• A01N25/00

  Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application {, e.g. seed treatment or sequential application}; Substances for reducing the noxious effect of the active ingredients to organisms other than pests · CPC title

• A01N2300/00

  Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48 · CPC title

• A01N25/32 Primary

  Ingredients for reducing the noxious effect of the active substances to organisms other than pests, e.g. toxicity reducing compositions, self-destructing compositions · CPC title

• A01N57/20

  containing acyclic or cycloaliphatic radicals · CPC title