Electric properties tomography imaging method and system

Patent metadata

Field	Value
Publication number	US-9638777-B2
Application number	US-201113522367-A
Country	US
Kind code	B2
Filing date	Jan 13, 2011
Priority date	Jan 18, 2010
Publication date	May 2, 2017
Grant date	May 2, 2017

Abstract

A magnetic resonance method of electric properties tomography imaging of an object includes applying an excitation RF field to the object via a coil at a first spatial coil position ( 402 ), acquiring resulting magnetic resonance signals via a receiving channel from the object, determining from the acquired magnetic resonance signals a first phase distribution and a first amplitude of a given magnetic field component of the excitation RF field of the coil at the first coil position ( 402 ), repeating these steps with a coil at a second different spatial coil position ( 404 ), to obtain a second phase distribution, determining a phase difference between the first and second phase distribution, determining a first and a second complex permittivity of the object, the first complex permittivity comprising the first amplitude of the given magnetic field component and the second complex permittivity comprising the second amplitude of the given magnetic field component and the phase difference, equating the first complex permittivity and the second complex permittivity for receiving a final equation and determining from the final equation a phase of the given magnetic field component for the first coil position ( 402 ).

First claim

The invention claimed is:

1. A magnetic resonance method of electric properties tomography of an object, the method comprising:
applying an imaging sequence that includes an excitation RF field to the object via a coil at a first spatial coil position, acquiring resulting magnetic resonance signals via a receiving channel from the object, determining from the acquired magnetic resonance signals a first phase distribution and a first amplitude of a first magnetic field component of the excitation RF field of the coil at the first coil position,
applying an excitation RF field to the object via a coil at a second spatial coil position, wherein the second spatial coil position is different from the first spatial coil position, acquiring resulting magnetic resonance signals via the receiving channel from the object, determining from the acquired magnetic resonance signals a second phase distribution and a second amplitude of a second magnetic field component of the excitation RF field of the coil at the second coil position,
determining a phase difference distribution between the first and second phase distribution,
determining a first and a second expression for the object's complex permittivity, the first expression for the complex permittivity expressed as a function of the first amplitude of the first magnetic field component and the second expression for the complex permittivity expressed as a function of the second amplitude of the second magnetic field component and the phase difference,
equating the first complex permittivity and the second complex permittivity for receiving a final equation and determining from the final equation a phase of the given magnetic field component for the first coil position; and
performing an electrical properties tomographic reconstruction using at least one of the first amplitude, the second amplitude, and the phase to generate an electrical properties tomographic image.

2. The method of claim 1 , wherein in the final equation the phase of the given magnetic field component for the first coil position is approximated by a parametrizable function.

3. The method of claim 1 , wherein the first magnetic field component is a positive circularly polarized magnetic field component of the excitation RF field at the first coil position, the method further including:
determining from the acquired magnetic resonance signals a negative circularly polarized magnetic field component at the first coil position.

4. The method of claim 1 , wherein the electrical properties tomographic reconstruction determines an anisotropy of a the complex permittivity of the object on the basis of the first or the second complex permittivity expression.

5. The method of claim 1 , wherein the first magnetic field component is a positive circularly polarized magnetic field component of the excitation RF field relative to the first coil position, the method further including:
determining a first geometrical symmetry plane of the object, such that the second coil position is a reflection of the first coil position relative to a symmetry plane,
determining a first map of the positive circularly polarized first magnetic field component of the excitation RF field at the second coil position,
determining a second map of a negative circularly polarized first magnetic field component at the first coil position by reflecting the first map relative to the symmetry plane.

6. A magnetic resonance method of electric properties tomography of an object, the method comprising:
applying an imaging sequence that includes an excitation RF field to the object via a coil at a first spatial coil position and acquiring first magnetic resonance signals,
applying the imaging sequence via a coil at a second spatial coil position and acquiring second magnetic resonance signals,
determining a geometrical symmetry plane of the object such that the second coil position is a reflection of the first coil position relative to said symmetry plane, with one or more processors,
from the excitation RF field at the second coil position, determining a first map of a positive circularly polarized magnetic field component relative to the second coil position, with the one or more processors,
determining a second map of a negative circularly polarized magnetic field component relative to the first coil position by reflecting the first map relative to the geometrical symmetry plane, with the one or more processors,
determining a negative circularly polarized magnetic field component relative to the first coil position from the second map, with the one or more processors,
from the first and second maps, generating a phase difference map, with the one or more processors, and
from the phase difference map, generating a specific absorption rate (SAR) map or image, with the one or more processors.

7. A method of electric properties tomography imaging of an object, the method comprising:
applying imaging sequences that include excitation RF fields to the object via first and second coils and acquiring resulting first and second magnetic resonance signals via a receiving channel from the object, the first and second coils being at different locations,
with one or more processors, determining from the first and second acquired magnetic resonance signals a magnetic field component of the excitation RF field of the coils, the magnetic field component including an amplitude component and a phase difference distribution,
with the one or more processors, setting the amplitude component to a constant value,
with the one or more processors, calculating a complex permittivity by dividing a surface volume integral of the gradient of said determined magnetic field phase difference distribution by a volume integral of said determined magnetic field phase difference distribution,
with the one or more processors, splitting said complex permittivity into a real part describing a permittivity component and an imaginary part describing a conductivity component,
with the one or more processors, calculating from the imaginary part of the conductivity component a conductivity distribution,
with the one or more processors, from the the conductivity distribution, constructing a specific absorption rate (SAR) map.

8. A non-transitory, tangible computer-readable medium carrying computer executable instructions to perform the method as claimed in claim 1 .

9. A magnetic resonance system for performing electric properties tomography imaging of an object, the system including at least one processor configured for:
controlling radio frequency and gradient coils to apply an imaging sequence that includes an excitation RF field to the object via a coil at a first spatial coil position, acquiring resulting magnetic resonance signals via a receiving channel from the object,
determining from the acquired magnetic resonance signals a first phase distribution and a first amplitude of a first magnetic field component of the excitation RF field of the coil at the first coil position,
controlling the radio frequency and gradient coils to apply an excitation RF field to the object via a coil at a second spatial coil position, wherein the second spatial coil position is different from the first spatial coil position, acquiring resulting magnetic resonance signals via the receiving channel from the object,
determining from the acquired magnetic resonance signals a second phase distribution and a second amplitude of a second magnetic field component of the excitation RF field of the coil at the second coil position,
determining a phase difference distribution between the first and second phase distributions,
determining from the first and second phase distributions, a first complex permittivity e

Assignees

• Voigt Tobias Ratko
• Katscher Ulrich
• Rozijn Thomas Hendrik
• Harvey Paul Royston
• Homann Hanno
• Findeklee Christian
• Hansis Eberhard Sebastian
• Koninklijke Philips Nv

Inventors

• Voigt Tobias Ratko
• Katscher Ulrich
• Rozijn Thomas Hendrik
• Harvey Paul Royston
• Homann Hanno
• Findeklee Christian
• Hansis Eberhard Sebastian

Classifications

• A61B5/055

  involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging · CPC title

• A61B5/0536

  Impedance imaging, e.g. by tomography · CPC title

• G01R33/246

  Spatial mapping of the RF magnetic field B1 · CPC title

• G01R33/443

  Assessment of an electric or a magnetic field, e.g. spatial mapping, determination of a B0 drift or dosimetry · CPC title

• G01R33/48 Primary

  NMR imaging systems · CPC title