High Fidelity Restriction Endonucleases
US-2024352437-A1 · Oct 24, 2024 · US
Compounds and methods for detection of enzymes that remove formyl, succinyl, methyl succinyl or myristoyl groups from ε-amino lysine moieties
US9637773B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9637773-B2 |
| Application number | US-93069311-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 13, 2011 |
| Priority date | Jan 13, 2011 |
| Publication date | May 2, 2017 |
| Grant date | May 2, 2017 |
How to read this patent
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
- Title
What the patent document calls the invention.
- Abstract
A short plain-language summary of the technical disclosure.
- Assignees and inventors
Who owns or filed the patent and who is credited as inventor.
- Key dates
Filing, priority, publication, and grant dates set the timeline.
- First independent claim
The legal scope of protection — read this for what is actually claimed.
- CPC / IPC classifications
Technology tags used to group this patent with similar filings.
- Citations and related patents
Prior art links and similar publications in this corpus.
Abstract
Official abstract text for this publication.
Provided is a compound that comprises the structure: where SIG is a signaling molecule and R 3 is a formyl, a succinyl, a methyl succinyl, or a myristoyl. Also provided is a kit is provided that comprises the above compound, with instructions for determining the presence of the enzyme. Additionally, a method is provided for determining whether a sample has an enzyme that removes a succinyl, a methyl succinyl, a formyl, or a myristoyl moiety from an ε-amino of a lysine. Also provided is a method of determining whether a molecule inhibits an enzyme that removes a succinyl, a methyl succinyl, a formyl, or a myristoyl moiety from an ε-amino of a lysine.
First claim
Opening claim text (preview).
What is claimed is: 1. A compound having the structure 2. A compound having the structure 3. A compound having the structure 4. A compound having the structure 5. A compound having the structure
Assignees
Inventors
Classifications
Spiro-condensed systems · CPC title
acting on amide bonds in linear amides (3.5.1) · CPC title
- C12Q1/34Primary
involving hydrolase · CPC title
Histone deacetylase (3.5.1.98), i.e. sirtuin deacetylase · CPC title
substituted in position 7 · CPC title
Patent family
Related publications grouped by family.
External sources
Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US9637773B2 cover?
- Provided is a compound that comprises the structure: where SIG is a signaling molecule and R 3 is a formyl, a succinyl, a methyl succinyl, or a myristoyl. Also provided is a kit is provided that comprises the above compound, with instructions for determining the presenc…
- Who is the assignee on this patent?
- Howitz Konrad T, Zhang Zhongda, Kisielewski Anne, and 3 more
- What technology area does this patent fall under?
- Primary CPC classification C12Q1/34. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue May 02 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).