Analysis system and production method of analysis image
US-2024290067-A1 · Aug 29, 2024 · US
US9632151B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9632151-B2 |
| Application number | US-201214125604-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 25, 2012 |
| Priority date | Jun 28, 2011 |
| Publication date | Apr 25, 2017 |
| Grant date | Apr 25, 2017 |
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A magnetic resonance measuring equipment capable of detecting a nuclear magnetic resonance signal with a higher sensitivity and a higher resolution in comparison with related magnetic resonance measuring equipment. The magnetic resonance measuring equipment modulates a nuclear magnetic resonance signal by applying a vibration (sonic wave) of a known frequency, which is higher than the frequency of the nuclear magnetic resonance signal, to an examination object, and detects the modulated signal by performing lock-in detection, which makes it possible that the magnetic resonance measuring equipment detects the nuclear magnetic resonance signal with a high sensitivity. In addition, after irradiating a local area of the object with an ultrasonic wave, and modulating the nuclear magnetic resonance signal derived from the irradiated local area, the magnetic resonance measuring equipment can detect the nuclear magnetic resonance signal with a high resolution.
Opening claim text (preview).
The invention claimed is: 1. A magnetic resonance measuring equipment comprising: a static magnetic field coil which generates a static magnetic field; a vibrator which applies a vibration to an examination object, the frequency of the vibration being higher than the frequency of a nuclear magnetic resonance signal generated from the examination object; a lock-in amplifier which performs lock-in detection using the frequency of the vibration as a reference signal; and a probe which detects the nuclear magnetic resonance signal generated from the examination object, wherein the nuclear magnetic resonance signal is modulated by the vibrator, and the modulated nuclear magnetic resonance signal is detected by the lock-in detection. 2. The magnetic resonance measuring equipment according to claim 1 , wherein the vibrator is a piezoelectric substance. 3. The magnetic resonance measuring equipment according to claim 1 , wherein the vibrator is a speaker. 4. The magnetic resonance measuring equipment according to claim 1 , wherein the vibrator is a motor. 5. The magnetic resonance measuring equipment according to claim 1 , wherein the probe is an induction coil. 6. The magnetic resonance measuring equipment according to claim 1 , wherein the probe is a superconducting quantum interference device (SQUID) magnetic flux meter. 7. The magnetic resonance measuring equipment according to claim 1 , wherein the vibrator is a converging ultrasonic wave transducer that generates a converging ultrasonic wave, and a spatial distribution of the nuclear magnetic resonance signal is detected through selectively vibrating a local area of the examination object by the converging ultrasonic wave transducer. 8. The magnetic resonance measuring equipment according to claim 1 , wherein an intensity of the static magnetic field is 1 mT (millitesla) or less. 9. A magnetic resonance measuring equipment comprising: a static magnetic field coil which generates a static magnetic field; a gradient magnetic field coil which generates a gradient magnetic field; an RF coil which generates an RF magnetic field; a vibrator which applies a vibration to an examination object, the frequency of the vibration being higher than the frequency of a nuclear magnetic resonance signal generated from the examination object; a probe to detect the nuclear magnetic resonance signal generated from the examination object; and a lock-in amplifier which performs lock-in detection using the frequency of the vibration as a reference signal, wherein the nuclear magnetic resonance signal is modulated by the piezoelectric substance, the nuclear magnetic resonance signal is detected by performing the lock-in detection on the modulated nuclear magnetic resonance signal, and the image of the examination object is depicted.
by using nuclear magnetic resonance (G01N24/12 takes precedence) · CPC title
Multimodal MR, e.g. MR combined with positron emission tomography [PET], MR combined with ultrasound or MR combined with computed tomography [CT] · CPC title
MR combined with ultrasound · CPC title
Constructional details, e.g. resonators {, specially adapted to MR} · CPC title
Image enhancement or correction, e.g. subtraction or averaging techniques {, e.g. improvement of signal-to-noise ratio and resolution} · CPC title
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