Method for producing halogenketones

Patent metadata

Field	Value
Publication number	US-9630898-B2
Application number	US-201415029594-A
Country	US
Kind code	B2
Filing date	Oct 20, 2014
Priority date	Oct 23, 2013
Publication date	Apr 25, 2017
Grant date	Apr 25, 2017

Abstract

The present invention describes a novel method for producing haloketones.

First claim

The invention claimed is:

1. Method for producing one or more haloketones of formula (I)
R 1 COCH 3   (I),

where
R 1 is haloalkyl,
comprising cleaving one or more ketoesters of formula (II)
R 1 COCH 2 COOR 2   (II),

where
R 2 is alkyl or benzyl and
R 1 is as defined above,
in the presence of phosphoric acid and without the addition of a carboxylic acid.

2. Method according to claim 1 , wherein
R 1 is selected from CF 3 , CF 2 H, or CF 2 Cl; and
R 2 is selected from methyl, ethyl, n-propyl, or benzyl.

3. Method according to claim 1 , wherein
R 1 is CF 2 H; and
R 2 is selected from methyl or ethyl.

4. Method according to claim 1 , wherein said method is carried out at a temperature of from 70° C. to 130° C.

5. Method according to claim 1 , wherein said method is carried out as a continuous operation.

6. A process for manufacturing a fungicidally active agent comprising the method according to claim 1 .

Assignees

• Bayer Cropscience Ag

Inventors

• Pazenok Sergii
• Funke Christian

Classifications

• C07C45/676 Primary

  by elimination of carboxyl groups · CPC title

• C07C49/167

  containing only fluorine as halogen · CPC title

• C07C49/16

  containing halogen · CPC title

• C07C45/86

  Use of additives, e.g. for stabilisation · CPC title