Pyrazolo pyrimidine derivatives and methods of use thereof
US-2016168151-A1 · Jun 16, 2016 · US
US9629843B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9629843-B2 |
| Application number | US-201514731778-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 5, 2015 |
| Priority date | Jul 8, 2008 |
| Publication date | Apr 25, 2017 |
| Grant date | Apr 25, 2017 |
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The present invention provides methods and compositions for selective modulation of certain protein kinases, and especially mTor complexes. The methods and compositions are particularly useful in inhibiting mTor selectively for therapeutic applications.
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What is claimed is: 1. A method for inhibiting cell proliferation of a leukemic cell comprising administration of an effective amount of a compound, or a pharmaceutical acceptable salt thereof, to said cell, wherein the compound has the formula:
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