Within-patient algorithm to predict heart failure decompensation

Patent metadata

Field	Value
Publication number	US-9629548-B2
Application number	US-201313870382-A
Country	US
Kind code	B2
Filing date	Apr 25, 2013
Priority date	Dec 27, 2006
Publication date	Apr 25, 2017
Grant date	Apr 25, 2017

Abstract

This document discusses, among other things, systems and methods for predicting heart failure decompensation using within-patient diagnostics. A method comprises detecting an alert status of each of one or more sensors; calculating an alert score by combining the detected alerts; and calculating a composite alert score, the composite alert score being indicative of a physiological condition and comprising a combination of two or more alert scores.

First claim

What is claimed is:

1. A patient device comprising:
an analysis module adapted to calculate a composite score indicative of a change of a physiological condition, the composite score being a combination of multiple scores, at least one of the multiple scores being a combination of multiple statuses, and at least one of the multiple statuses being from one of a plurality of detectors and indicative of an occurrence of an event; and
a communication module adapted to provide an indication of the change of the physiological condition based on a comparison between the composite score and a threshold.

2. The patent device of claim 1 , wherein the status includes a value that reflects a comparison between a parameter detected at a respective one of the plurality of detectors and a corresponding threshold for the parameter.

3. The patent device of claim 1 , wherein the parameter includes sensed physiological data.

4. The patent device of claim 1 , wherein at least one of the plurality of detectors includes an implantable medical device.

5. The patent device of claim 1 , wherein the patient device includes an implantable medical device.

6. The patent device of claim 1 , wherein the analysis module automatically determines the threshold based on an input parameter.

7. The patent device of claim 6 , wherein the input parameter includes one or more of a time, a number of detectors, a patient characteristic, a clinician preference, or a previous threshold.

8. The patent device of claim 1 , wherein the analysis module establishes the threshold using a constant false alarm rate technique.

9. A non-transitory machine-readable medium comprising instructions, which when executed on a machine, cause the machine to:
calculate a composite score indicative of a change of a physiological condition, the composite score being a combination of multiple scores, at least one of the multiple scores being a combination of multiple statuses, and at least one of the multiple statuses being from one of a plurality of detectors and indicative of an occurrence of an event; and
provide an indication of the change of the physiological condition based on a comparison between the composite score and a threshold.

10. The non-transitory machine-readable medium of claim 9 , comprising instructions to receive at least one of the multiple scores from at least one of the plurality of detectors.

11. The non-transitory machine-readable medium of claim 9 , wherein the status includes a value that reflects a comparison between a parameter detected at a respective one of the plurality of detectors and a corresponding threshold for the parameter.

12. The non-transitory machine-readable medium of claim 11 , wherein the parameter includes sensed physiological data.

13. The non-transitory machine-readable medium of claim 9 , comprising instructions to automatically determine the threshold based on an input parameter.

14. The non-transitory machine-readable medium of claim 13 , wherein the input parameter includes one or more of a time, a number of detectors, a patient characteristic, a clinician preference, or a previous threshold.

15. The non-transitory machine-readable medium of claim 9 , comprising instructions to establish the threshold using a constant false alarm rate technique.

16. A method comprising:
calculating, by a computational system, a composite score indicative of a change of a physiological condition, the composite score being a combination of multiple scores, at least one of the multiple scores being a combination of multiple statuses, and at least one of the multiple statuses being from one of a plurality of detectors and indicative of an occurrence of an event; and
providing an indication of the change of the physiological condition based on a comparison between the composite score and a threshold.

17. The method of claim 16 , comprising receiving at least one of the multiple scores from at least one of the plurality of detectors.

18. The method of claim 16 , wherein the status includes a value that reflects a comparison between a physiological parameter detected at a respective one of the plurality of detectors and a corresponding threshold for the physiological parameter.

19. The method of claim 16 , automatically determining the threshold based on an input parameter, wherein the input parameter includes one or more of a time, a number of detectors, a patient characteristic, a clinician preference, or a previous threshold.

20. The method of claim 16 , comprising establishing the threshold using a constant false alarm rate technique.

Assignees

• Cardiac Pacemakers Inc

Inventors

• Sachanandani Haresh G
• Peterson Jon
• Cazares Shelley M
• Sweeney Robert J
• Stalsberg Kevin John

Classifications

• A61B5/0031 Primary

  Implanted circuitry · CPC title

• A61N1/37252

  Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data · CPC title

• A61B5/02455

  provided with high/low alarm devices · CPC title

• A61N1/3627

  for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy · CPC title

• A61B5/145

  Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value {; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue} (non-radiation detecting or locating of foreign bodies in blood A61B5/06) · CPC title