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US9624202B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9624202-B2 |
| Application number | US-201615271581-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 21, 2016 |
| Priority date | Feb 15, 2013 |
| Publication date | Apr 18, 2017 |
| Grant date | Apr 18, 2017 |
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- Title
What the patent document calls the invention.
- Abstract
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- Assignees and inventors
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- Key dates
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- First independent claim
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- CPC / IPC classifications
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- Citations and related patents
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Abstract
Official abstract text for this publication.
Disclosed are compounds having the formula: wherein X, Y, Z 1 , Z 2 , Z 3 , Z 4 , R 5 , R A , m, A. L, and B are as defined herein, and methods of making and using the same.
First claim
Opening claim text (preview).
What is claimed is: 1. A compound which is: or a tautomer thereof, or a pharmaceutically acceptable salt thereof. 2. A pharmaceutical composition comprising the compound, or a tautomer thereof, or pharmaceutically acceptable salt thereof, according to claim 1 and one or more pharmaceutically acceptable excipients. 3. A method of treating ulcerative colitis comprising administering a therapeutically effective amount of the compound, or a tautomer thereof, or pharmaceutically acceptable salt thereof, according to claim 1 to a human in need thereof. 4. A method of treating Crohn's disease comprising administering a therapeutically effective amount of the compound, or a tautomer thereof, or pharmaceutically acceptable salt thereof, according to claim 1 to a human in need thereof. 5. A method of treating rheumatoid arthritis comprising administering a therapeutically effective amount of the compound, or a tautomer thereof, or pharmaceutically acceptable salt thereof, according to claim 1 to a human in need thereof. 6. A method of treating psoriasis comprising administering a therapeutically effective amount of the compound, or a tautomer thereof, or pharmaceutically acceptable salt thereof, according to claim 1 to a human in need thereof. 7. A method of treating spondyloarthritis comprising administering a therapeutically effective amount of the compound, or a tautomer thereof, or pharmaceutically acceptable salt thereof, according to claim 1 to a human in need thereof. 8. A method of treating SoJIA comprising administering a therapeutically effective amount of the compound, or a tautomer thereof, or pharmaceutically acceptable salt thereof, according to claim 1 to a human in need thereof. 9. A method of treating osteoarthritis comprising administering a therapeutically effective amount of the compound, or a tautomer thereof, or pharmaceutically acceptable salt thereof, according to claim 1 to a human in need thereof. 10. A method of treating multiple sclerosis comprising administering a therapeutically effective amount of the compound, or a tautomer thereof, or pharmaceutically acceptable salt thereof, according to claim 1 to a human in need thereof. 11. A method of treating sepsis comprising administering a therapeutically effective amount of the compound, or a tautomer thereof, or pharmaceutically acceptable salt thereof, according to claim 1 to a human in need thereof. 12. A method of treating ischemia reperfusion injury of solid organs comprising administering a therapeutically effective amount of the compound, or a tautomer thereof, or pharmaceutically acceptable salt thereof, according to claim 1 to a human in need thereof. 13. A method of treating systemic inflammatory response syndrome comprising administering a therapeutically effective amount of the compound, or a tautomer thereof, or pharmaceutically acceptable salt thereof, according to claim 1 to a human in need thereof. 14. A compound which is: or a tautomer thereof. 15. A pharmaceutical composition comprising the compound, or a tautomer thereof, according to claim 14 and one or more pharmaceutically acceptable excipients. 16. A method of treating ulcerative colitis comprising administering a therapeutically effective amount of the compound, or a tautomer thereof, according to claim 14 to a human in need thereof. 17. A method of treating Crohn's disease comprising administering a therapeutically effective amount of the compound, or a tautomer thereof, according to claim 14 to a human in need thereof. 18. A method of treating rheumatoid arthritis comprising administering a therapeutically effective amount of the compound, or a tautomer thereof, according to claim 14 to a human in need thereof. 19. A method of treating psoriasis comprising administering a therapeutically effective amount of the compound, or a tautomer thereof, according to claim 14 to a human in need thereof. 20. A method of treating spondyloarthritis comprising administering a therapeutically effective amount of the compound, or a tautomer thereof, according to claim 14 to a human in need thereof. 21. A method of treating SoJIA comprising administering a therapeutically effective amount of the compound, or a tautomer thereof, according to claim 14 to a human in need thereof. 22. A method of treating osteoarthritis comprising administering a therapeutically effective amount of the compound, or a tautomer thereof, according to claim 14 to a human in need thereof. 23. A method of treating multiple sclerosis comprising administering a therapeutically effective amount of the compound, or a tautomer thereof, according to claim 14 to a human in need thereof. 24. A method of treating sepsis comprising administering a therapeutically effective amount of the compound, or a tautomer thereof, according to claim 14 to a human in need thereof. 25. A method of treating ischemia reperfusion injury of solid organs comprising administering a therapeutically effective amount of the compound, or a tautomer thereof, according to claim 14 to a human in need thereof. 26. A method of treating systemic inflammatory response syndrome comprising administering a therapeutically effective amount of the compound, or a tautomer thereof, according to claim 14 to a human in need thereof.
Assignees
Inventors
Classifications
for hyperglycaemia, e.g. antidiabetics · CPC title
Antiallergic agents (antiasthmatic agents A61P11/06; ophthalmic antiallergics A61P27/14) · CPC title
Immunomodulators · CPC title
Drugs for immunological or allergic disorders · CPC title
Immunosuppressants, e.g. drugs for graft rejection · CPC title
Patent family
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Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US9624202B2 cover?
- Disclosed are compounds having the formula: wherein X, Y, Z 1 , Z 2 , Z 3 , Z 4 , R 5 , R A , m, A. L, and B are as defined herein, and methods of making and using the same.
- Who is the assignee on this patent?
- Glaxosmithkline Ip Dev Ltd
- What technology area does this patent fall under?
- Primary CPC classification C07D417/12. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Apr 18 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 3 related publications on this page (citations in our corpus or others sharing the same primary CPC).