Process for optical coherence tomography and apparatus for optical coherence tomography

Patent metadata

Field	Value
Publication number	US-9618322-B2
Application number	US-201114368765-A
Country	US
Kind code	B2
Filing date	Dec 28, 2011
Priority date	Dec 28, 2011
Publication date	Apr 11, 2017
Grant date	Apr 11, 2017

Abstract

In a process for optical coherence tomography a plurality of first OCT slice images, in each first slice image representing a different slice of an object, are recorded. Subsequently a reference figure that is representative of the three-dimensional contour of at least one structural feature of the object in a given three-dimensional coordinate system is ascertained by feature recognition of the at least one structural feature in the first slice images. Then a plurality of second OCT slice images, each second slice image representing a different slice of the object, are recorded. At least a fraction of the second slice images are displaced in the coordinate system until each second slice image is in feature overlap with the reference figure. Lastly, a set of three-dimensional OCT image data is generated at least from the feature-overlapped second slice images.

First claim

The invention claimed is:

1. Process for optical coherence tomography, comprising:
recording a plurality of first OCT slice images, each first slice image representing a different slice of an object;
ascertaining a reference figure that is representative of the three-dimensional contour of at least one structural feature of the object in a given three-dimensional coordinate system by feature recognition of the at least one structural feature in the first slice images;
recording a plurality of second OCT slice images, each second slice image representing a different slice of the object, a time period for recording a second slice image is longer than a time period for recording a first slice image;
displacing at least a fraction of the slice images in the coordinate system until each second slice image is in feature overlap with the reference figure; and
generating a set of three-dimensional OCT image data at least from the feature-overlapped second slice images.

2. Process according to claim 1 , wherein the number of first slice images is smaller than the number of second slice images.

3. Process according to claim 1 , wherein for each slice image a plurality of A-scans of the object are recorded, the number of A-scans for the first slice images being in each instance smaller than for the second slice images.

4. Process according to claim 1 , wherein the first slice images are recorded by means of B-scans that are distributed over the object in a regular pattern.

5. Process according to claim 1 , wherein the first slice images are recorded by means of B-scans that are distributed in a cross-grid pattern.

6. Process according to claim 1 , wherein the first slice images are recorded in such a distribution pattern that points of intersection of the first slice images with the reference figure are situated, distributed substantially at equal spacings, along the reference figure and/or that the number n of points of intersection at which the reference figure intersects the first slice images in each instance at an angle within the range of more than 30° and less than 60° in relation to the surface normals of the respective slice image amounts to at least 2(N−2), where N is the number of first slice images, and/or that the number n of points of intersection at which the reference figure intersects the first slice images suffices for describing the geometry of the reference figure after the reference figure has been adapted to the first slice images.

7. Process according to claim 1 , wherein the second slice images are recorded by means of B-scans that are distributed over the object in an irregular pattern.

8. Process according to claim 7 , wherein the irregular pattern includes a cross-grid pattern, the grid-line density of which in a central region of the reference figure is lower than in a region of the reference figure remote from the centre.

9. Process according to claim 7 , wherein the irregular pattern includes at least two cross-grid patterns placed over one another in angle-offset manner, whereby in particular the pattern includes two cross-grid patterns placed over one another in angle-offset manner with an angle of about 45° or includes three cross-grid patterns placed over one another in angle-offset manner with an angle of about 60° .

10. Process according to claim 1 , wherein the ascertaining of the reference figure includes an adapting of at least one circular figure to feature positions of the at least one structural feature in the first slice images.

11. Process according to claim 1 , wherein the object is a human eye and the at least one structural feature includes an inner iris margin and/or an outer iris margin of the eye and/or a limbus of the eye.

12. Apparatus for optical coherence tomography, comprising an OCT image-acquisition unit and a computer arrangement that has been set up to:
control the OCT image-acquisition unit in such a manner that the OCT image-acquisition unit records a plurality of first OCT slice images, each first slice image representing a different slices of an object;
ascertain a reference figure that is representative of the three-dimensional contour of at least one structural feature of the object in a given three-dimensional coordinate system by feature recognition of the at least one structural feature in the first slice images;
control the OCT image-acquisition unit in such a manner that the OCT image-acquisition unit records a plurality of second OCT slice images, each second slice image representing a different slice of the object, a time period for recording a second slice image is longer than a time period for recording a first slice image;
displace at least a fraction of the second slice images in the coordinate system until each second slice image is in feature overlap with the reference figure, figure; and
generate a set of three-dimensional OCT image data at least from the feature-overlapped second slice images.

13. Apparatus according to claim 12 , wherein the OCT image-acquisition unit has been set up to record a number of first slice images and a number of second slice images, the number of first slice images being smaller than the number of second slice images.

14. Apparatus according to claim 12 , wherein the OCT image-acquisition unit has been set up to record for each slice image a plurality of A-scans of the object, the number of A-scans for the first slice images being in each instance smaller than for the second slice images.

15. Apparatus according to claim 12 , wherein the OCT image-acquisition unit has been set up to record the first slice images by means of B-scans that are distributed over the object in a regular pattern.

16. Apparatus according to claim 12 , wherein the OCT image-acquisition unit has been set up to record the first slice images by means of B-scans that are distributed in a cross-grid pattern.

17. Apparatus according to claim 12 , wherein the OCT image-acquisition unit has been set up to record the first slice images in such a distribution pattern that points of intersection of the first slice images with the reference figure are situated, distributed substantially at equal spacings, along the reference figure and/or that the number n of points of intersection at which the reference figure intersects the first slice images in each instance at an angle within the range of more than 30° and less than 60° in relation to the surface normal of the respective slice image amounts to at least 2(N−2), where N is the number of first slice images, and/or that the number n of points of intersection at which the reference figure intersects the first slice images suffices for describing the geometry of the reference figure after the reference figure has been adapted to the first slice images.

18. Apparatus according to claim 12 , wherein the OCT image-acquisition unit has been set up to record the second slice images by means of B-scans that are distributed over the object in an irregular pattern.

19. Apparatus according to claim 18 , wherein the OCT image-acquisition unit has been set up to record the second slice images in accordance with the irregular pattern, the irregular pattern including a cross-grid pattern, the grid-line density of which in a central region of the reference figure is lower than in a region of the reference figure remote from the centre.

20. Apparatus according to claim 18 , wherein the OCT image-acquisition unit has been set up to record the second slice images in accordance with the irregular pattern, the irregular pattern includ

Assignees

• Jeglorz Tobias
• Massow Ole
• Wisweh Henning
• Wavelight Gmbh

Inventors

• Jeglorz Tobias
• Massow Ole
• Wisweh Henning

Classifications

• G06V10/75

  Organisation of the matching processes, e.g. simultaneous or sequential comparisons of image or video features; Coarse-fine approaches, e.g. multi-scale approaches; using context analysis; Selection of dictionaries · CPC title

• A61B3/102 Primary

  for optical coherence tomography [OCT] · CPC title

• G01B9/02041 Primary

  characterised by particular imaging or detection techniques · CPC title

• G06F18/22

  Matching criteria, e.g. proximity measures · CPC title

• A61B5/0066

  Optical coherence imaging · CPC title