Heterocyclic modulators of lipid synthesis
US-2024400552-A1 · Dec 5, 2024 · US
US9617249B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9617249-B2 |
| Application number | US-201313753356-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 29, 2013 |
| Priority date | May 30, 2008 |
| Publication date | Apr 11, 2017 |
| Grant date | Apr 11, 2017 |
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Embodiments herein provide compounds and methods of making and using such compounds for prevention and treatment of multidrug resistant bacteria. In particular, embodiments are directed to anti-bacterial agents from benzo[d]heterocyclic scaffolds for prevention and treatment of multidrug resistant bacteria.
Opening claim text (preview).
What is claimed is: 1. A method of treating a drug-resistant bacterial strain, comprising: administering a compound to an individual infected with or suspected of being infected with a methicillin-resistant Staphylococcus aureus strain, a vancomycin-resistant Enterococcus strain, or a linezolid-resistant Enterococcus strain, wherein the bacterial strain is killed or inhibited from growing, wherein the compound is one of the following compounds: 2. The method of claim 1 , wherein the compound is: 3. The method of claim 1 , wherein the compound is: 4. The method of claim 1 , wherein the compound is:
directly linked by a ring-member-to-ring-member bond · CPC title
containing nitrogen {having a Si-N linkage} · CPC title
condensed with carbocyclic rings, e.g. benzimidazoles · CPC title
Ortho-condensed systems · CPC title
attached in position 5 · CPC title
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