Pipettor, reagent, and wash solution heater

Patent metadata

Field	Value
Publication number	US-9616426-B2
Application number	US-201314423412-A
Country	US
Kind code	B2
Filing date	Aug 23, 2013
Priority date	Aug 29, 2012
Publication date	Apr 11, 2017
Grant date	Apr 11, 2017

Abstract

A heater for heating fluidic elements and fluids is provided. The heater quickly and efficiently heats elements and samples without occupying a lot of space in in vitro diagnostic environments. The heater includes an induction coil, sized and configured to allow for a fluidic element to be placed therein, and induction circuitry coupled to the induction coil that facilitates induction heating through electromagnetic induction. A current is generated to pass through the induction coil, creating a field within the induction coil that generates heat that is transferrable to conductive objects placed within the field. In this manner, heat is transferred to the fluidic element and to fluids in contact with the fluidic element.

First claim

I claim:

1. A heater for heating fluidic elements and fluids in an in vitro diagnostics (IVD) environment, the heater comprising:
an induction coil sized and configured to allow for a fluidic element to be placed therein;
induction circuitry coupled to the induction coil and configured to generate a current to pass through the induction coil, thereby creating a field within the induction coil that generates heat transferrable to the fluidic element placed therein;
a sensing coil sized and configured to allow for the fluidic element to be placed therein; and
level-sensing circuitry coupled to the sensing coil and configured to impose a signal on the fluidic element when placed in the sensing coil and detect a change in the imposed signal, wherein the change in the imposed signal serves as an indication that the fluidic element is in contact with a fluid;
wherein the fluidic element is configured to aspirate a sample fluid from the fluid contained within a sample tube; and
wherein the heat is transferred to the fluidic element prior to aspiration, during aspiration, and following aspiration depending upon an order in which the fluidic element is placed within the induction coil and aspirates the sample fluid.

2. The heater of claim 1 , further comprising:
a sensor configured to detect a temperature of the fluidic element placed within the induction coil.

3. The heater of claim 1 , wherein the current generated to pass through the induction coil comprises a radio-frequency alternating current, and wherein the field created comprises a radio-frequency magnetic field.

4. A system for use in an in vitro diagnostics (IVD) environment for heating fluidic elements and fluids, the system comprising:
a sample tube configured to contain therein a fluid;
a fluidic element configured to aspirate a sample fluid from the fluid contained within the sample tube, the fluidic element coupled to a transfer arm movable to access the sample tube; and
a heater in a position accessible by the fluidic element, the heater comprising:
an induction coil sized and configured to allow for the fluidic element to be placed therein;
induction circuitry coupled to the induction coil and configured to generate a current to pass through the induction coil, thereby creating a field within the induction coil that generates heat transferrable to the fluidic element placed therein;
a sensing coil sized and configured to allow for the fluidic element to be placed therein; and
level-sensing circuitry coupled to the sensing coil and configured to impose a signal on the fluidic element when placed in the sensing coil and detect a change in the imposed signal, wherein the change in the imposed signal serves as an indication that the fluidic element is in contact with the fluid contained within the sample tube;

wherein heat is imparted to the sample fluid from the heat transferred to the fluidic element prior to aspiration, during aspiration, and following aspiration depending upon an order in which the fluidic element is placed within the induction coil and aspirates the sample fluid.

5. The system of claim 4 , further comprising:
a sensor configured to detect a temperature of the fluidic element placed within the induction coil, the sensor coupled to at least one of the fluidic element and the heater.

6. The system of claim 4 , further comprising:
a sensor coupled to a dispensing unit, the sensor configured to detect a temperature of a portion of the sample fluid dispensed from the fluidic element to the dispensing unit.

7. The system of claim 4 , further comprising:
a washing unit configured to wash the fluidic element after dispensing the sample fluid, wherein the heater generates a high temperature heat transferrable to the fluidic element placed within the induction coil to eliminate carry-over on the fluidic element.

8. The system of claim 4 , wherein the fluidic element is configured to move between the sample tube and the heater.

9. The system of claim 4 , wherein the heater is attached to the fluidic element.

10. A method of heating fluidic elements and fluids in an in vitro diagnostics (IVD) environment, the method comprising:
providing a sample tube containing therein a fluid;
providing a fluidic element configured to aspirate a sample fluid from the fluid contained within the sample tube and configured to fit within an induction coil of a heater and a sensing coil, the fluidic element coupled to a transfer arm movable to access the sample tube;
applying, through induction circuitry coupled to the induction coil, a current to pass through the induction coil, thereby creating a field within the induction coil that generates heat transferrable to the fluidic element placed therein;
detecting by level-sensing circuitry coupled to the sensing coil that the fluidic element is in contact with the fluid contained within the sample tube, wherein the level-sensing circuitry is configured to impose a signal on the fluidic element and detect a change in the imposed signal, wherein the change in the imposed signal serves as an indication that the fluidic element is in contact with the fluid; and
aspirating, by the fluidic element, the sample fluid from the sample tube, wherein heat is imparted to the sample fluid from the heat transferred to the fluidic element prior to aspiration, during aspiration, and following aspiration depending upon an order in which the fluidic element is placed within the induction coil and aspirates the sample fluid.

11. The method of claim 10 , further comprising:
detecting, via a sensor coupled to at least one of the fluidic element and the heater, a temperature of the fluidic element placed within the induction coil.

12. The method of claim 10 , further comprising:
detecting, via a sensor coupled to a dispensing unit, a temperature of a portion of the sample fluid dispensed from the fluidic element to the dispensing unit.

13. The method of claim 10 , further comprising:
washing, via a washing unit, the fluidic element after dispensing the sample fluid; and
inserting the fluidic element into the induction coil of the heater, wherein the heater generates a high temperature heat transferrable to the fluidic element placed within the induction coil to eliminate carry-over on the fluidic element.

14. The method of claim 10 , further comprising:
prior to aspirating, by the fluidic element, the sample fluid from the sample tube, removing the fluidic element from the induction coil of the heater.

15. The method of claim 10 , wherein the heater is attached to the fluidic element.

Assignees

• Siemens Healthcare Diagnostics Inc

Inventors

• Dulaff Paul

Classifications

• B01L3/0275

  Interchangeable or disposable dispensing tips · CPC title

• G01N1/44

  Sample treatment involving radiation, e.g. heat · CPC title

• G01N2035/00425

  Heating or cooling means associated with pipettes or the like, e.g. for supplying sample/reagent at given temperature · CPC title

• B01L2300/1816

  using induction heating · CPC title

• B01L7/00 Primary

  Heating or cooling apparatus (autoclaves B01J3/04); Heat insulating devices · CPC title