Structures of langya virus fusion protein ectodomain and immunogenic compositions derived therefrom
US-2024358817-A1 · Oct 31, 2024 · US
US9612200B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9612200-B2 |
| Application number | US-201414522847-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 24, 2014 |
| Priority date | Sep 9, 2011 |
| Publication date | Apr 4, 2017 |
| Grant date | Apr 4, 2017 |
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There is provided a particle detector that can increase a detection sensitivity to fluorescence emitted from biogenic particles. A particle detector for detecting biogenic particles includes a substrate having a principal surface and configured to collect the biogenic particles on the principal surface, a light emitting element configured to irradiate particles collected on the principal surface with excitation light, and a light receiving element configured to receive fluorescence emitted from the particles when the particles are irradiated with the excitation light from the light emitting element. An optical axis of the Fresnel lens and a ray direction of the excitation light intersect with each other. The principal surface is a mirror surface.
Opening claim text (preview).
The invention claimed is: 1. A particle detector that detects biogenic particles, comprising: a collecting member including a principal surface that collects the biogenic particles on the principal surface; an excitation optical system that irradiates the particles collected on the principal surface with excitation light at an angle not normal to the principal surface; and a light receiving optical system that receives fluorescence emitted from the particles when the particles are irradiated with the excitation light from the excitation optical system, wherein an optical axis of the light receiving optical system and a ray direction of the excitation light intersect with each other, the principal surface is a mirror surface, the light receiving optical system includes a light collecting lens, and the light collecting lens includes a matrix and an absorbent dispersed in the matrix that absorbs the excitation light. 2. The particle detector according to claim 1 , wherein the light collecting lens is a Fresnel lens. 3. The particle detector according to claim 1 , wherein the following relationship is established: T =( B /cos θ+ L )/2 tan θ where θ represents an incident angle of the excitation light on the principal surface, L represents a diameter of the light collecting lens, T represents a distance between the light collecting lens and the principal surface, and B represents a diameter of the excitation light. 4. The particle detector according to claim 1 , wherein the material that absorbs the excitation light has a property to act as a highpass filter that cuts off light with a wavelength of a predetermined threshold value or less and transmits light with a wavelength of the predetermined threshold value or more. 5. The particle detector according to claim 4 , wherein the material that absorbs the excitation light cuts off light with a peak value of optical spectral intensity of the excitation light and transmits light with a peak value of optical spectral intensity of the fluorescence.
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