Compositions and methods for targeted delivery to cells
US-2024390271-A1 · Nov 28, 2024 · US
Protein scaffolds for antibody mimics and other binding proteins
US9605039B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9605039-B2 |
| Application number | US-54331606-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 3, 2006 |
| Priority date | Dec 10, 1998 |
| Publication date | Mar 28, 2017 |
| Grant date | Mar 28, 2017 |
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Abstract
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Disclosed herein are proteins that include an immunoglobulin fold and that can be used as scaffolds. Also disclosed herein are nucleic acids encoding such proteins and the use of such proteins in diagnostic methods and in methods for evolving novel compound-binding species and their ligands.
First claim
Opening claim text (preview).
What is claimed is: 1. An isolated protein comprising a domain derived from the tenth module of the human fibronectin type III ( 10 Fn3), wherein said domain comprises the amino acid sequence selected from the group consisting of: SEQ ID NOs: 80, 96, 67, 127, 128, 135, and 140. 2. The protein of claim 1 , wherein said protein is a monomer under physiological conditions. 3. The protein of claim 1 , wherein said protein is fused to a secon…
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Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
- C07K14/47Primary
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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- What does patent US9605039B2 cover?
- Disclosed herein are proteins that include an immunoglobulin fold and that can be used as scaffolds. Also disclosed herein are nucleic acids encoding such proteins and the use of such proteins in diagnostic methods and in methods for evolving novel compound-binding species and their ligands.
- Who is the assignee on this patent?
- Lipovsek Dasa, Wagner Richard W, Kuimelis Robert G, and 1 more
- What technology area does this patent fall under?
- Primary CPC classification C07K14/47. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Mar 28 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).