Bioactive terpolymer compositions and methods of making and using same
US-2016082110-A1 · Mar 24, 2016 · US
Terpolymers as pressure-sensitive adhesives
US9598532B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9598532-B2 |
| Application number | US-201113221389-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 30, 2011 |
| Priority date | Aug 30, 2010 |
| Publication date | Mar 21, 2017 |
| Grant date | Mar 21, 2017 |
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- Title
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- Abstract
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Abstract
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Disclosed herein are terpolymers that can function as pressure-sensitive adhesives. The disclosed articles comprise the terpolymers adhered to a release liner. The disclosed implant devices comprise the pressure-sensitive adhesive terpolymer adhered to a surface thereof. The pressure-sensitive adhesive terpolymer can promote adhesion of the implant device to a location in a subject.
First claim
Opening claim text (preview).
What is claimed is: 1. An article, comprising: a pressure-sensitive adhesive (PSA) having a first adhesive surface and an opposing second adhesive surface, the pressure-sensitive adhesive (PSA) comprises a poly(D,L-lactide-co-glycolide-co-ε-caprolactone) having a molecular weight (M w ) of from 100,000 to 140,000 Daltons and a polydispersity index (PDI) of less than 2.0; wherein the poly(D,L-lactide-co-glycolide-co-ε-caprolactone) exhibits storage modulus (G′) values of from about 1.5×10 5 Pa to about 5.5×10 5 Pa, over a frequency of from about 0.1 to about 1 Hz; and exhibits storage modulus (G′) values of from about 1.0×10 6 Pa to about 4.0×10 6 Pa, over a frequency of from about 10 2 to about 10 4 Hz at 30° C.; the poly(D,L-lactide-co-glycolide-co-ε-caprolactone) comprising from 50 to 60 mol % caprolactone; and a bioactive agent selected from the group consisting of gentamicin, tobramycin, rifampin, and minocycline, or combinations thereof; and a release liner, wherein the release liner fully covers the first adhesive surface and the second adhesive surface of the pressure-sensitive adhesive. 2. The article of claim 1 , wherein the pressure-sensitive adhesive (PSA) consists of the poly(D,L-lactide-co-glycolide-co-ε-caprolactone). 3. The article of claim 1 , the pressure-sensitive adhesive comprising a planar film. 4. The article of claim 1 , wherein the pressure-sensitive adhesive is divided into a plurality of discrete units separated from one another, the plurality of units held together by the release liner.
Assignees
Inventors
Classifications
Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title
Drugs for skeletal disorders · CPC title
Drugs for disorders of the alimentary tract or the digestive system · CPC title
for treating wounds, ulcers, burns, scars, keloids, or the like · CPC title
including components having same physical characteristic in differing degree · CPC title
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- What does patent US9598532B2 cover?
- Disclosed herein are terpolymers that can function as pressure-sensitive adhesives. The disclosed articles comprise the terpolymers adhered to a release liner. The disclosed implant devices comprise the pressure-sensitive adhesive terpolymer adhered to a surface thereof. The pressure-sensitive adhesive terpolymer can promote adhesion of the implant device to a location in a subject.
- Who is the assignee on this patent?
- Bowman Howard, Hudson Bruce W, Surmodics Inc
- What technology area does this patent fall under?
- Primary CPC classification C08G63/08. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Mar 21 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 3 related publications on this page (citations in our corpus or others sharing the same primary CPC).