Microfabricated fluidic circuit elements and applications

Patent metadata

Field	Value
Publication number	US-9593698-B2
Application number	US-201314072243-A
Country	US
Kind code	B2
Filing date	Nov 5, 2013
Priority date	Apr 6, 2001
Publication date	Mar 14, 2017
Grant date	Mar 14, 2017

Abstract

A microfabricated fluidic unidirectional valve includes a microfabricated elastomer material having a flow through channel. The microfabricated fluidic unidirectional valve also includes an elastomer flap attached to the elastomer material in the flow through channel. The elastomer flap forms a seal in the flow through channel to prevent fluid from flowing in a first direction through the flow through channel and to allow fluid flow in a second direction through the flow through channel.

First claim

What is claimed is:

1. A microfabricated fluidic device comprising:
first and second elastomeric layers each having one or more recesses formed therein, wherein the first and second elastomeric layers are bonded together;
one or more input channels formed by the recesses in the first and second elastomeric layers;
at least one output channel formed by the recesses in the first and second elastomeric layers; and
a plurality of elastomeric chambers formed by the recesses in the first and second elastomeric layers,
wherein the elastomeric chambers are configured to form a microfabricated fluidic analog element operable to perform an analog mathematical function by elastically responding to the one or more analog input signals in the one or more input channels to provide an analog output signal in the output channel, wherein a continuous change in at least one of the analog input signals causes a corresponding continuous change in the analog output signal.

2. The microfabricated fluidic device of claim 1 wherein the microfabricated fluidic analog element is operable to perform addition on the input signals to provide the output signals.

3. The microfabricated fluidic device of claim 1 wherein the microfabricated fluidic analog element is operable to perform subtraction on the input signals to provide the output signals.

4. The microfabricated fluidic device of claim 1 wherein the microfabricated fluidic analog element is operable to perform multiplication on the input signals to provide the output signals.

5. The microfabricated fluidic device of claim 1 wherein the microfabricated fluidic analog element is operable to perform division on the input signals to provide the output signals.

6. The microfabricated fluidic device of claim 1 wherein the microfabricated fluidic analog element is operable to perform an integration on the input signals to provide the output signals.

7. The microfabricated fluidic device of claim 1 wherein the microfabricated fluidic analog element is operable to perform a differentiation on the input signals to provide the output signals.

8. The microfabricated fluidic device of claim 1 wherein the microfabricated fluidic analog element is operable to perform a regulation of the input signals to provide the output signals.

9. The microfabricated fluidic device of claim 1 wherein the microfabricated fluidic analog element is operable to perform an amplification on the input signals to provide the output signals.

10. The microfabricated fluidic device of claim 1 wherein the recesses each have a dimension between 0.1 μm and 1000 μm.

11. The microfabricated fluidic device of claim 1 wherein the first and second elastomeric layers are each configured to flex in response to the analog input signals to cooperatively generate the analog output signal.

12. The microfabricated fluidic device of claim 1 wherein the analog mathematical function is linear.

Assignees

• Fluidigm Corp

Inventors

• Fernandes David
• Chou Hou-Pu
• Unger Marc A

Classifications

• A61M2206/22

  eliminating pulsatile flows, e.g. by the provision of a dampening chamber · CPC title

• Y10T137/7879

  Resilient material valve · CPC title

• F16K99/0001

  Microvalves (microdevices B81B1/00; manufacture or treatment of devices or systems in or on a substrate B81C1/00; microfluidic structures B01L3/5027; micropumps F04B19/006) · CPC title

• F16K2099/0084

  Chemistry or biology, e.g. "lab-on-a-chip" technology · CPC title

• B01L2400/0638

  membrane valves, flap valves · CPC title